Chorioamnionitis: Difference between revisions
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Revision as of 14:41, 24 August 2020
Background
- Ascending bacterial infection leading to inflammation of the membranes and placenta
- Also called intraamniotic infection
Microbiology
- Usually polymicrobial
- Ureaplasma urealyticum (47%)
- Mycoplasma hominis (30%)
- Gardnerella vaginalis (25%)
- Bacteroides species (30%)
- Group B streptococcus (15%)
- Escherichia coli (8%)
Epidemiology
- 1 to 4% of all birth
- More common with preterm delivery, PROM, prolonged labour, smoking/alcohol/drug use, multiple vaginal examination, internal monitoring of labour, bacterial vaginosis, colonization by group B streptococcus, and nulliparity
Clinical Manifestations
- Fever, tenderness over the uterine fundus, maternal tachycardia, fetal tachycardia
- May have purulent or malodorous amniotic fluid
- Can be complicated by endometritis, pelvic abscess, surgical site infection, bacteremia, postpartum hemorrhage, and poor neonatal outcomes
