Burkholderia cepacia complex: Difference between revisions
From IDWiki
Burkholderia cepacia complex
Content deleted Content added
Created page with "== Background == * Stain::Gram-negative Cellular shape::bacillus * Multiple mechanisms of resistance: ** β-lactamases ** RND efflux pumps ** Altered LPS conferring p..." |
(No difference)
|
Revision as of 15:17, 15 August 2020
Background
- Gram-negative bacillus
- Multiple mechanisms of resistance:
- β-lactamases
- RND efflux pumps
- Altered LPS conferring polymixin resistance
- Gyrase mutations conferring fluoroquinolone resistance
Management
- Should be guided by antimicrobial susceptibility testing
- Antibiotic options include:
- TMP-SMX (preferred, if susceptible)
- Ceftazidime and ceftazidime-avibactam
- Meropenem and imipenem
- Minocycline
