Meningitis: Difference between revisions

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== Background ==
==Background==


* Inflammation or infection of the meninges and subarachnoid spact
*Inflammation or infection of the meninges and subarachnoid spact
* May be acute, subacute, or [[Chronic meningitis|chronic]]
*May be acute, subacute, or [[Chronic meningitis|chronic]] (≥4 weeks)
* May be caused by [[Bacterial meningitis|bacteria]], [[Viral meningitis|viruses]], [[Fungal meningitis|fungi]], [[Parasitic meningitis|parasites]], or [[Aseptic meningitis|non-infectious causes]]
*May be caused by [[Bacterial meningitis|bacteria]], [[Viral meningitis|viruses]], [[Fungal meningitis|fungi]], [[Parasitic meningitis|parasites]], or [[Aseptic meningitis|non-infectious causes]]


== Diagnosis ==
==Diagnosis==


* Typically confirmed by lumbar puncture demonstrating pleocytosis, with or without MRI brain
*Typically confirmed by lumbar puncture demonstrating pleocytosis, with or without MRI brain


{| class="wikitable"
{| class="wikitable"
!Parameter
!Parameter
!Normal
!Normal
!Bacterial
![[Bacterial meningitis|Bacterial]]
!Viral
![[Viral meningitis|Viral]]
!Tuberculous
![[Tuberculous meningitis|Tuberculous]]
!Fungal
![[Fungal meningitis|Fungal]]
|-
|-
|Opening pressure
|Opening pressure
|12-20 cmH<sub>2</sub>O
|12 to 20 cmH<sub>2</sub>O
|raised
|raised
|normal or raised
|normal or raised
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|Protein
|Protein
|0.4 g/L
|0.4 g/L
|high
|raised
|somewhat high
|slightly raised
|very high
|markedly raised
|high
|raised
|-
|-
|Glucose
|Glucose

Latest revision as of 21:10, 12 August 2020

Background

Diagnosis

  • Typically confirmed by lumbar puncture demonstrating pleocytosis, with or without MRI brain
Parameter Normal Bacterial Viral Tuberculous Fungal
Opening pressure 12 to 20 cmH2O raised normal or raised raised raised
Appearance clear cloudy clear clear or cloudy clear or cloudy
WBC count <5 >100 5 to 100 5 to 500 5 to 500
Differential PMN lymphocyte lymphocyte lymphocyte
Protein 0.4 g/L high somewhat high very high high
Glucose >2/3 of plasma very low normal to low very low low