Meningitis: Difference between revisions
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==Background== |
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* |
*Inflammation or infection of the meninges and subarachnoid spact |
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* |
*May be acute, subacute, or [[Chronic meningitis|chronic]] (≥4 weeks) |
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* |
*May be caused by [[Bacterial meningitis|bacteria]], [[Viral meningitis|viruses]], [[Fungal meningitis|fungi]], [[Parasitic meningitis|parasites]], or [[Aseptic meningitis|non-infectious causes]] |
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==Diagnosis== |
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*Typically confirmed by lumbar puncture demonstrating pleocytosis, with or without MRI brain |
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{| class="wikitable" |
{| class="wikitable" |
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!Parameter |
!Parameter |
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!Normal |
!Normal |
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!Bacterial |
![[Bacterial meningitis|Bacterial]] |
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!Viral |
![[Viral meningitis|Viral]] |
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!Tuberculous |
![[Tuberculous meningitis|Tuberculous]] |
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!Fungal |
![[Fungal meningitis|Fungal]] |
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|- |
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|Opening pressure |
|Opening pressure |
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|12 |
|12 to 20 cmH<sub>2</sub>O |
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|raised |
|raised |
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|normal or raised |
|normal or raised |
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|Protein |
|Protein |
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|0.4 g/L |
|0.4 g/L |
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|high |
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|raised |
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|somewhat high |
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|slightly raised |
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|very high |
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|markedly raised |
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|high |
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|raised |
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|- |
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|Glucose |
|Glucose |
Latest revision as of 21:10, 12 August 2020
Background
- Inflammation or infection of the meninges and subarachnoid spact
- May be acute, subacute, or chronic (≥4 weeks)
- May be caused by bacteria, viruses, fungi, parasites, or non-infectious causes
Diagnosis
- Typically confirmed by lumbar puncture demonstrating pleocytosis, with or without MRI brain
Parameter | Normal | Bacterial | Viral | Tuberculous | Fungal |
---|---|---|---|---|---|
Opening pressure | 12 to 20 cmH2O | raised | normal or raised | raised | raised |
Appearance | clear | cloudy | clear | clear or cloudy | clear or cloudy |
WBC count | <5 | >100 | 5 to 100 | 5 to 500 | 5 to 500 |
Differential | PMN | lymphocyte | lymphocyte | lymphocyte | |
Protein | 0.4 g/L | high | somewhat high | very high | high |
Glucose | >2/3 of plasma | very low | normal to low | very low | low |