Maribavir: Difference between revisions

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* Class is benzimidazole riboside
* Class is benzimidazole riboside
* Mechanism of action is inhibition of UL97-mediated phosphorylation of nuclear lamin A/C
* Mechanism of action is inhibition of UL97-mediated phosphorylation of nuclear lamin A/C
* Main indication is [[CMV]] prophylaxis in solid-organ transplant
* Main indication is [[CMV]] prophylaxis in solid organ transplant


== Further Reading ==
== Further Reading ==
* Maribavir for Refractory or Resistant Cytomegalovirus Infections in Hematopoietic-cell or Solid-organ Transplant Recipients: A Randomized, Dose-ranging, Double-blind, Phase 2 Study. ''Clin Infect Dis''. 2019;68(8):1255–1264. DOI: [https://doi.org/10.1093/cid/ciy706 10.1093/cid/ciy706]
* Maribavir for Refractory or Resistant Cytomegalovirus Infections in Hematopoietic-cell or Solid organ Transplant Recipients: A Randomized, Dose-ranging, Double-blind, Phase 2 Study. ''Clin Infect Dis''. 2019;68(8):1255–1264. DOI: [https://doi.org/10.1093/cid/ciy706 10.1093/cid/ciy706]


[[Category:Antivirals]]
[[Category:Antivirals]]

Latest revision as of 01:03, 7 August 2020

  • Class is benzimidazole riboside
  • Mechanism of action is inhibition of UL97-mediated phosphorylation of nuclear lamin A/C
  • Main indication is CMV prophylaxis in solid organ transplant

Further Reading

  • Maribavir for Refractory or Resistant Cytomegalovirus Infections in Hematopoietic-cell or Solid organ Transplant Recipients: A Randomized, Dose-ranging, Double-blind, Phase 2 Study. Clin Infect Dis. 2019;68(8):1255–1264. DOI: 10.1093/cid/ciy706