Bacterial meningitis (IDSA 2004): Difference between revisions
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Revision as of 14:51, 2 August 2020
Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM, Whitley RJ. Practice guidelines for the management of bacterial meningitis. Clin Infect Dis. 2004 Nov 1;39(9):1267-84. Epub 2004 Oct 6. doi: 10.1086/425368
Table 4: Empiric Treatment
| Population | Common pathogens | Antimicrobial therapy |
|---|---|---|
| Age | ||
| <1 month | GBS, E.coli, Listeria, Klebsiella | amp + cefotax, or amp + AG |
| 1-23 months | S.pneumo, N.mening, GBS, H.flu, E.coli | vanco + 3G ceph |
| 2-50 years | N.mening, S.pneumo | vanco + 3G ceph |
| >50 years | S.pneumo, N.mining, Listeria, GNBs | vanco + 3G ceph + amp |
| Head trauma | ||
| Basilar skull fracture | S.pneumo, H.flu, GAS | vanco + 3G ceph |
| Penetrating trauma | Staph.aureus, CoNS, GNBs | vanco + cefep, or vanco + ceftaz, or vanco + mero |
| Post-neurosurgery | GNBs, Staph.aureus, CoNS | vanco + cefep, or vanco + ceftaz, or vanco + mero |
| CSF shunt | CoNS, Staph,aureus, GNBs, P.acnes | vanco + cefep, or vanco + ceftaz, or vanco + mero |
