Chloroquine: Difference between revisions

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* Antimalarial
*Antimalarial
* Active against intra-erythrocytic ''Plasmodium'', by binding haematin in the parasite digestive vacuole
*Active against intra-erythrocytic ''[[Plasmodium species|Plasmodium]]'', by binding haematin in the parasite digestive vacuole
* Retinal toxicity at 100 g total ingestion
*Retinal toxicity at 100 g total ingestion
** So if on weekly prophylaxis for 5 years, they should get twice-annual retinal screening
**So if on weekly prophylaxis for 5 years, they should get twice-annual retinal screening
* Risk of seizures, psychosis, and worsening psoriasis
*Risk of [[Seizure|seizures]], [[psychosis]], and worsening [[psoriasis]]


[[Category:Antiparasitics]]
[[Category:Antiparasitics]]

Latest revision as of 13:59, 2 August 2020

  • Antimalarial
  • Active against intra-erythrocytic Plasmodium, by binding haematin in the parasite digestive vacuole
  • Retinal toxicity at 100 g total ingestion
    • So if on weekly prophylaxis for 5 years, they should get twice-annual retinal screening
  • Risk of seizures, psychosis, and worsening psoriasis