Bacillus anthracis: Difference between revisions
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Bacillus anthracis
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*Causes '''anthrax''' |
*Causes '''anthrax''' |
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==Background== |
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===Microbiology=== |
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*[[Stain::Gram-positive]] [[Cellular shape::bacillus]] that is distinguished from other [[Bacillus species]] by being non-motile and non-hemolytic |
*[[Stain::Gram-positive]] [[Cellular shape::bacillus]] that is distinguished from other [[Bacillus species]] by being [[Motility::non-motile]] and [[Hemolysis::non-hemolytic]] |
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*Colonies are gray, flat, and may have a "Medusa head" or "comet" appearance |
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==Clinical Manifestations== |
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===Cutaneous anthrax=== |
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*Caused by inoculation of spores into soft tissue |
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*Incubation period of 2 to 5 days |
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*Lesion develops at site of inoculation, starting as erythemaous papule, then ulceration, then eschar |
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*May progress to sepsis |
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===Pulmonary anthrax=== |
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*Caused by inhalation of spores |
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*Also known as woolsorter's disease |
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*Start with malaise, fever, and nonproductive cough, followed by respiratory distress, severe pulmonary edema, and death |
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===Gastrointestinal anthrax=== |
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*Caused by ingestion of spores |
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*Infects oropharynx or abdomen |
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*Causes sepsis{{DISPLAYTITLE:''Bacillus anthracis''}} |
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<br />{{DISPLAYTITLE:''Bacillus anthracis''}} |
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[[Category:Gram-positive bacilli]] |
[[Category:Gram-positive bacilli]] |
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Revision as of 00:49, 28 July 2020
- Causes anthrax
Background
Microbiology
- Gram-positive bacillus that is distinguished from other Bacillus species by being non-motile and non-hemolytic
- Colonies are gray, flat, and may have a "Medusa head" or "comet" appearance
Clinical Manifestations
Cutaneous anthrax
- Caused by inoculation of spores into soft tissue
- Incubation period of 2 to 5 days
- Lesion develops at site of inoculation, starting as erythemaous papule, then ulceration, then eschar
- May progress to sepsis
Pulmonary anthrax
- Caused by inhalation of spores
- Also known as woolsorter's disease
- Start with malaise, fever, and nonproductive cough, followed by respiratory distress, severe pulmonary edema, and death
Gastrointestinal anthrax
- Caused by ingestion of spores
- Infects oropharynx or abdomen
- Causes sepsis
References
- ^ Tucker Maxson, Thiphasone Kongphet-Tran, Thitipong Mongkolrattanothai, Tatiana Travis, Katherine Hendricks, Corinne Parker, Heather P McLaughlin, Julia Bugrysheva, Frank Ambrosio, Pierre Michel, Blake Cherney, Christine Lascols, David Sue. Systematic Review of In Vitro Antimicrobial Susceptibility Testing for Bacillus anthracis, 1947–2019. Clinical Infectious Diseases. 2022;75(Supplement_3):S373-S378. doi:10.1093/cid/ciac520.
