Hyperthyroidism: Difference between revisions

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** Lithium
** Lithium


== Clinical Presentation ==
== Clinical Manifestations ==


=== Biochemical ===
=== Biochemical ===

Revision as of 12:37, 23 July 2020

Differential Diagnosis

  • Graves disease (autoimmune)
  • Thyroiditis
    • Viral (painful, subacute)
    • Autoimmune
      • Transient (painless)
      • Post-partum thyroiditis (painless)
  • Toxic nodule
  • Toxic multinodular goitre
  • Iatrogenic
    • Amiodarone
    • Lithium

Clinical Manifestations

Biochemical

  • Laboratory dysfunction only

Subclinical

  • Progresses to symptomatic hyperthyroidism in 25% by 5 years

Clinical

  • History
    • Heat intolerance
    • Weight loss
    • Anxiety
    • Emotional ability
    • Weakness
    • Tremor
    • Palpitations
    • Increased perspiration
    • Distractibility
  • Signs & Symptoms
    • Atrial fibrillation

Graves Disease

  • Signs and symptoms of hyperthyroidism
  • Diffuse goitre
  • Proptosis, palpebral swelling
  • Diffuse dermopathy

Investigations

  • Labs
    • TSH; if low, repeat and add free T3 and free T4
  • Imaging
  • Other