Blastocystis hominis: Difference between revisions
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Blastocystis hominis
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| + | == Background == |
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| + | === Epidemiology === |
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| + | * Worldwide, but varies by subtype |
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| + | ** Subtype 3 most common worldwide in human |
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| + | ** Subtype 4 is in Europe |
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| + | * Prevalence higher in developing than developed countries |
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| + | |||
| + | == Clinical Manifestations == |
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| + | * Unclear if it causes a clinical syndrome; may be strain-dependent |
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| + | * Has been implicated in acute diarrhea, chronic diarrhea, bloating, flatulence, abdominal cramping, and fatigue, as well as irritable bowel syndrome |
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| + | |||
| + | == Diagnosis == |
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| + | * Stool microscopy with trichrome stain |
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| + | * In vitro cell culture |
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| + | * PCR is standard |
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| + | |||
| + | == Management == |
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| + | * Eliminate all other causes of symptoms |
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| + | * If still symptomatic, can consider treatment |
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| + | ** [[Is treated by::Nitazoxanide]] 500 mg po bid for 3 days |
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| + | ** Can also try: [[Is treated by::metronidazole]] 750 mg po tid for 10 days, [[Is treated by::trimethoprim-sulfamethoxazole]] DS 1 tab po bid for 7 days, and [[Is treated by::iodoquinol]] 650 mg po tid for 20 days |
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| + | ** Unclear which, if any, is helpful |
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{{DISPLAYTITLE:''Blastocystis hominis''}} |
{{DISPLAYTITLE:''Blastocystis hominis''}} |
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[[Category:Protozoa]] |
[[Category:Protozoa]] |
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Latest revision as of 00:28, 23 July 2020
Background
Epidemiology
- Worldwide, but varies by subtype
- Subtype 3 most common worldwide in human
- Subtype 4 is in Europe
- Prevalence higher in developing than developed countries
Clinical Manifestations
- Unclear if it causes a clinical syndrome; may be strain-dependent
- Has been implicated in acute diarrhea, chronic diarrhea, bloating, flatulence, abdominal cramping, and fatigue, as well as irritable bowel syndrome
Diagnosis
- Stool microscopy with trichrome stain
- In vitro cell culture
- PCR is standard
Management
- Eliminate all other causes of symptoms
- If still symptomatic, can consider treatment
- Nitazoxanide 500 mg po bid for 3 days
- Can also try: metronidazole 750 mg po tid for 10 days, trimethoprim-sulfamethoxazole DS 1 tab po bid for 7 days, and iodoquinol 650 mg po tid for 20 days
- Unclear which, if any, is helpful
