Dientamoeba fragilis: Difference between revisions
From IDWiki
Dientamoeba fragilis
(Created page with "== Further Reading == * Dientamoeba fragilis, the Neglected Trichomonad of the Human Bowel. ''Clin Microbiol Rev''. 2016;29(3):553–580. DOI: [https://doi.org/10.1128/CMR.000...") |
m (Text replacement - "Clinical Presentation" to "Clinical Manifestations") |
||
| (3 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
== Background == |
|||
=== Microbiology === |
|||
* Gastrointestinal flagellated protozoan parasite |
|||
=== Life Cycle === |
|||
* Unclear, but may inoculate humans via [[pinworm]] eggs |
|||
== Clinical Manifestations == |
|||
* There exists some debate about its pathogenicity |
|||
* Many cases are asymptomatic and incidental on stool ova & parasite |
|||
* Attributable symptoms, when present, vague abdominal pain, bloating, diarrhea, fatigue, weight loss and anorexia |
|||
== Management == |
|||
* Look for coinfection with ''[[Enterobius vermicularis]]'' |
|||
* If symptomatic, treat with: |
|||
** [[Is treated by::Iodoquinol]] 650 mg orally three times daily for 20 days |
|||
** [[Is treated by::Paromomycin]] 25–35 mg per kg per day orally, in three divided doses, for 7 days |
|||
** [[Is treated by::Metronidazole]] 500–750 mg orally three times daily for 10 days, though this may be associated with a higher rate of recurrence |
|||
== Further Reading == |
== Further Reading == |
||
* Dientamoeba fragilis, the Neglected Trichomonad of the Human Bowel. ''Clin Microbiol Rev''. 2016;29(3):553–580. DOI: [https://doi.org/10.1128/CMR.00076-15 10.1128/CMR.00076-15] |
* ''Dientamoeba fragilis'', the Neglected Trichomonad of the Human Bowel. ''Clin Microbiol Rev''. 2016;29(3):553–580. DOI: [https://doi.org/10.1128/CMR.00076-15 10.1128/CMR.00076-15] |
||
* ''Dientamoeba fragilis'': A harmless commensal or a mild pathogen? ''Paed Child Health''. 1998;3(2):81-82. DOI: [https://doi.org/10.1093/pch/3.2.81 10.1093/pch/3.2.81] |
|||
* A Review of the Clinical Manifestations of Dientamoebiasis. ''Am J Trop Med Hyg''. 2010;82(4):614-619. DOI: [https://doi.org/10.4269/ajtmh.2010.09-0478 10.4269/ajtmh.2010.09-0478] |
|||
{{DISPLAYTITLE:''Dientamoeba fragilis''}} |
{{DISPLAYTITLE:''Dientamoeba fragilis''}} |
||
Latest revision as of 12:12, 14 July 2020
Background
Microbiology
- Gastrointestinal flagellated protozoan parasite
Life Cycle
- Unclear, but may inoculate humans via pinworm eggs
Clinical Manifestations
- There exists some debate about its pathogenicity
- Many cases are asymptomatic and incidental on stool ova & parasite
- Attributable symptoms, when present, vague abdominal pain, bloating, diarrhea, fatigue, weight loss and anorexia
Management
- Look for coinfection with Enterobius vermicularis
- If symptomatic, treat with:
- Iodoquinol 650 mg orally three times daily for 20 days
- Paromomycin 25–35 mg per kg per day orally, in three divided doses, for 7 days
- Metronidazole 500–750 mg orally three times daily for 10 days, though this may be associated with a higher rate of recurrence
Further Reading
- Dientamoeba fragilis, the Neglected Trichomonad of the Human Bowel. Clin Microbiol Rev. 2016;29(3):553–580. DOI: 10.1128/CMR.00076-15
- Dientamoeba fragilis: A harmless commensal or a mild pathogen? Paed Child Health. 1998;3(2):81-82. DOI: 10.1093/pch/3.2.81
- A Review of the Clinical Manifestations of Dientamoebiasis. Am J Trop Med Hyg. 2010;82(4):614-619. DOI: 10.4269/ajtmh.2010.09-0478
