Escherichia coli: Difference between revisions

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Escherichia coli
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== Background ==
== Background ==
=== Microbiology ===
=== Microbiology ===
* Lactose-fermenting [[Has Gram stain::Gram-negative]] [[Has shape::bacillus]] within the [[Enterobacteriaceae]]
* Lactose-fermenting [[Has Gram stain::Gram-negative]] [[Cellular shape::bacillus]] within the [[Enterobacteriaceae]]
* Member of commensal gut flora
* Member of commensal gut flora



Revision as of 19:30, 5 July 2020

Background

Microbiology

Classification

  • Has multiple pathotypes
    • Extraintestinal pathogenic E. coli (ExPEC): causes UTI and neonatal meningitis
      • Strains that cause neonatal meningitis are more likely to produce K1 capsule and S fimbriae
    • Enteropathogenic E. coli (EPEC): produces localize adherence pilus, causes severe acute watery diarrhea that can become chronic
    • Enterotoxigenic E. coli (ETEC): produces enterotoxins, causes acute watery diarrhea
    • Enterhemorrhagic E.coli (EHEC) and Shiga toxin-producing E. coli (STEC): produces Shiga (or related) toxins, causes watery and bloody diarrhea and can lead to HUS
    • Enteroaggregative E. coli (EAEC): produces adherence factors, causes mucoid diarrhea that can become chronic
    • Enteroinvasive E. coli (EIEC): spreads cell-to-cell, causes watery diarrhea or dysentery
    • Diffuse-adhering E. coli (DAEC): causes diarrhea