Myeloproliferative disorders: Difference between revisions
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Criteria
| Criterion | PV | ET | PMF |
|---|---|---|---|
| CBC | Hb >165 (men) or >160 (women) Hct >48% (men) or 49% (women) RBC mass >25% predicted |
Plts ≥450 | WBC ≥11 (minor) Anemia (minor) |
| Bone marrow | Panmyelosis | Megakeryocytosis | Megakaryocytosis ± fibrosis |
| JAK2 | JAK2 or JAK2 exon 12 | JAK2, CALR, or MPL | JAK2, CALR, or MPL |
| Other | Low serum epo (minor) | Not otherwise explained Clonal marker (minor) Not reactive thrombocytosis |
Not otherwise explained Palpable spleen (minor) High LDH (minor) |
