Monoclonal gammopathy of unknown significance

Also see [[|Multiple myeloma]]

Definition

• Proliferation of a single gamma globulin

Differential Diagnosis

• Neoplasm
  • Lymphoma
    • Lymphoplasmacytic lymphoma (Waldenstrom's macroglobulinemia)
    • Chronic lymphocytic leukemia
    • Follicular lymphoma
    • Diffuse large B-cell lymphoma
  • Multiple myeloma
• Infection
  • Hepatitis C
  • HIV
• Connective tissue diseases
  • Rheumatoid arthritis (RA)
  • Systemic lupus erythematosus (SLE)

Management

• Depends on underlying health