Eosinophilia

Differential Diagnosis

• Hematologic
  • Primary: esopinophilic leukemia, CMML, HES
  • Secondary: Non-Hodgkin's and Hodgkin's lymphomas
• Infectious
  • Parasitic infections including Strongyloides
• Inflammatory
  • Eosinophilic pneumonia
  • Eosinophilic esophagitis
  • Eosinophilic myositis
  • Eosinophilic granulomatosis with polyantiitis (eGPA or Churg-Strauss)
• Endocrine
  • Addison's disease
• Allergy
  • Atopy
  • Asthma
• Drugs
  • Drug reaction with eosinophilia and systemic symptoms (DRESS)

Investigations

• CBC
• Stool O&P and Strongy serology
• ANCAs
• Review current medications