Balamuthia mandrillaris: Difference between revisions
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Balamuthia mandrillaris
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==Clinical Presentation== |
==Clinical Presentation== |
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* Causes '''granulomatous amebic encephalitis (GAE)''' alone, skin lesions followed by GAE, or (rarely) skin lesions alone |
* Causes '''granulomatous amebic encephalitis (GAE)''' alone, skin lesions followed by GAE, or (rarely) skin lesions alone |
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** Characterized by progressive hemorrhagic necrosis of brain, with 90% mortality |
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** Fever, headache, altered mentation), vomiting, lethargy, seizures, and weakness |
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* Often preceded by skin lesions, typically affecting the nose and cheeks, that can progress over months |
* Often preceded by skin lesions, typically affecting the nose and cheeks, that can progress over months |
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* Difficult to treat, with high mortality |
* Difficult to treat, with high mortality |
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Revision as of 23:59, 3 June 2020
Background
Microbiology
- One of the free-living amoebae
Epidemiology
- Present in soil
- More common in US and South America
- More common in Hispanics
Clinical Presentation
- Causes granulomatous amebic encephalitis (GAE) alone, skin lesions followed by GAE, or (rarely) skin lesions alone
- Characterized by progressive hemorrhagic necrosis of brain, with 90% mortality
- Fever, headache, altered mentation), vomiting, lethargy, seizures, and weakness
- Often preceded by skin lesions, typically affecting the nose and cheeks, that can progress over months
- Difficult to treat, with high mortality
