Balamuthia mandrillaris: Difference between revisions

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Balamuthia mandrillaris
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==Background==
* Environmental protozoan parasite that causes '''granulomatous amebic encephalitis (GAE)'''
===Microbiology===
* GAE is characterized by progressive hemorrhagic necrosis of brain
* One of the [[free-living amoebae]]

===Epidemiology===
* Present in soil
* More common in US and South America
* More common in Hispanics

==Clinical Presentation==
* Causes '''granulomatous amebic encephalitis (GAE)''' alone, skin lesions followed by GAE, or (rarely) skin lesions alone
* GAE is characterized by progressive hemorrhagic necrosis of brain, with 90% mortality
* Often preceded by skin lesions, typically affecting the nose and cheeks, that can progress over months
* Difficult to treat, with high mortality


{{DISPLAYTITLE:''Balamuthia mandrillaris''}}
{{DISPLAYTITLE:''Balamuthia mandrillaris''}}

Revision as of 23:51, 3 June 2020

Background

Microbiology

Epidemiology

  • Present in soil
  • More common in US and South America
  • More common in Hispanics

Clinical Presentation

  • Causes granulomatous amebic encephalitis (GAE) alone, skin lesions followed by GAE, or (rarely) skin lesions alone
  • GAE is characterized by progressive hemorrhagic necrosis of brain, with 90% mortality
  • Often preceded by skin lesions, typically affecting the nose and cheeks, that can progress over months
  • Difficult to treat, with high mortality