Escherichia coli: Difference between revisions

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Escherichia coli
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== Background ==
* [[Has Gram stain::Gram-negative]] bacillus
=== Microbiology ===
* Lactose-fermenting [[Has Gram stain::Gram-negative]] [[Has shape::bacillus]] within the [[Enterobacteriaceae]]
* Member of commensal gut flora
* Member of commensal gut flora
* Has multiple '''pathotypes'''
** Extraintestinal pathogenic ''E. coli'' (ExPEC): causes UTI and neonatal meningitis
*** Strains that cause neonatal meningitis are more likely to produce K1 capsule and S fimbriae
** Enterotoxigenic ''E. coli'' (ETEC): produces enterotoxins, causes acute watery diarrhea
** Enteropathogenic ''E. coli'' (EPEC): produces localize adherence pilus, causes severe acute watery diarrhea that can become chronic
** Enterhemorrhagic ''E.coli'' (EHEC) and Shiga toxin-producing ''E. coli'' (STEC): produces Shiga toxins, causes watery and bloody diarrhea and can lead to HUS
** Enteroaggregative ''E. coli'' (EAEC): produces adherence factors, causes mucoid diarrhea that can become chronic
** Enteroinvasive ''E. coli'' (EIEC): spreads cell-to-cell, causes watery diarrhea or dysentery
** Diffuse-adhering ''E. coli'' (DAEC): causes diarrhea


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{{DISPLAYTITLE:''Escherichia coli''}}

Revision as of 01:17, 14 November 2019

Background

Microbiology

  • Lactose-fermenting Gram-negative bacillus within the Enterobacteriaceae
  • Member of commensal gut flora
  • Has multiple pathotypes
    • Extraintestinal pathogenic E. coli (ExPEC): causes UTI and neonatal meningitis
      • Strains that cause neonatal meningitis are more likely to produce K1 capsule and S fimbriae
    • Enterotoxigenic E. coli (ETEC): produces enterotoxins, causes acute watery diarrhea
    • Enteropathogenic E. coli (EPEC): produces localize adherence pilus, causes severe acute watery diarrhea that can become chronic
    • Enterhemorrhagic E.coli (EHEC) and Shiga toxin-producing E. coli (STEC): produces Shiga toxins, causes watery and bloody diarrhea and can lead to HUS
    • Enteroaggregative E. coli (EAEC): produces adherence factors, causes mucoid diarrhea that can become chronic
    • Enteroinvasive E. coli (EIEC): spreads cell-to-cell, causes watery diarrhea or dysentery
    • Diffuse-adhering E. coli (DAEC): causes diarrhea