Schistosoma: Difference between revisions

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Schistosoma
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= ''Schistosoma'' spp. (schistosomiasis) =
 
 
== Definition ==
 
 
 
* Infection with a species of the genus ''Schistosoma''
 
* Infection with a species of the genus ''Schistosoma''
   
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* Increased risk of squamous cell carcinoma, which increase with young age at infection, duration of infection, high burden of infection, and bladder wall fibrosis
 
* Increased risk of squamous cell carcinoma, which increase with young age at infection, duration of infection, high burden of infection, and bladder wall fibrosis
   
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{{DISPLAYTITLE:''Schistosoma'' species}}
== Further Reading ==
 
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[[Category:Parasites]]

Revision as of 07:29, 16 August 2019

  • Infection with a species of the genus Schistosoma

Species

  • S. mansoni: liver and gut
  • S. haematobium: GU/pelvis
  • S. japonicum: liver and gut
  • S. mekongi: Mekong basin

Risk Factors

  • Fresh water exposure in endemic countries

Clinical Presentation

Investigations

  • Labs
    • CBC, showing eosinophilia
    • Schisto serology (only positive 6 weeks after infection)
    • Egg detection in stool, urine, semen, or tissue biopsy
  • Imaging
    • Eggs can cause granulomatous disease in various organs
    • Bladder polyps and obstruction may be seen on ultrasound

Management

  • Acute
    • Praziquantel 40mg/kg/d
      • Can cause nausea, dizziness, and fever
  • Chronic
    • Prevention

Prognosis

  • Increased risk of squamous cell carcinoma, which increase with young age at infection, duration of infection, high burden of infection, and bladder wall fibrosis

References

  1. ^  Archana Asundi, Alina Beliavsky, Xing Jian Liu, Arash Akaberi, Guido Schwarzer, Zeno Bisoffi, Ana Requena-Méndez, Ian Shrier, Christina Greenaway. Prevalence of strongyloidiasis and schistosomiasis among migrants: a systematic review and meta-analysis. The Lancet Global Health. 2019;7(2):e236-e248. doi:10.1016/s2214-109x(18)30490-x.