Ciprofloxacin: Difference between revisions
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== Background == |
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* Fluoroquinolone antibiotic with [[Antipseudomonal antibiotics|antipseudomonal activity]] |
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* Inhibits [[Inhibits::CYP1A2]] |
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== Clinical Breakpoints == |
== Clinical Breakpoints == |
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** MIC of 1 previously reported as susceptible but had reports of reduced susceptibility in practice |
** MIC of 1 previously reported as susceptible but had reports of reduced susceptibility in practice |
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** New cutoff is 0.5 for susceptibility |
** New cutoff is 0.5 for susceptibility |
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== Safety == |
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* Similar to other fluoroquinolones |
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* QTc prolongation may not be as much of a clinical concern at usual doses[[CiteRef::liu2026th]] |
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[[Category:Fluoroquinolones]] |
[[Category:Fluoroquinolones]] |
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Latest revision as of 16:27, 6 April 2026
Background
- Fluoroquinolone antibiotic with antipseudomonal activity
- Inhibits CYP1A2
Clinical Breakpoints
- For the Enterobacteriaceae changed recently
- MIC of 1 previously reported as susceptible but had reports of reduced susceptibility in practice
- New cutoff is 0.5 for susceptibility
Safety
- Similar to other fluoroquinolones
- QTc prolongation may not be as much of a clinical concern at usual doses1
References
- ^ Weber Liu, Hugh G Dickson, Hany Dimitri, Yashodha Shankar Pani, Jayanathi Ramanathan, Dana West, Sarah Tima, Winston Thai. The effect of oral ciprofloxacin at conventional doses on the QT interval in a tertiary outpatient setting. Journal of Antimicrobial Chemotherapy. 2026;81(3). doi:10.1093/jac/dkag020.
