Meningitis: Difference between revisions
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*Inflammation or infection of the meninges and subarachnoid spact |
*Inflammation or infection of the meninges and subarachnoid spact |
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*May be acute, subacute, or [[Chronic meningitis|chronic]] |
*May be acute, subacute, or [[Chronic meningitis|chronic]] (≥4 weeks) |
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*May be caused by [[Bacterial meningitis|bacteria]], [[Viral meningitis|viruses]], [[Fungal meningitis|fungi]], [[Parasitic meningitis|parasites]], or [[Aseptic meningitis|non-infectious causes]] |
*May be caused by [[Bacterial meningitis|bacteria]], [[Viral meningitis|viruses]], [[Fungal meningitis|fungi]], [[Parasitic meningitis|parasites]], or [[Aseptic meningitis|non-infectious causes]] |
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**See also [[aseptic meningitis]] |
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==Diagnosis== |
==Diagnosis== |
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*Typically confirmed by lumbar puncture demonstrating pleocytosis, with or without MRI brain |
*Typically confirmed by lumbar puncture demonstrating [[CSF pleocytosis|pleocytosis]], with or without MRI brain |
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{| class="wikitable" |
{| class="wikitable" |
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!Parameter |
!Parameter |
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!Normal |
!Normal |
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!Bacterial |
![[Bacterial meningitis|Bacterial]] |
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!Viral |
![[Viral meningitis|Viral]] |
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!Tuberculous |
![[Tuberculous meningitis|Tuberculous]] |
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!Fungal |
![[Fungal meningitis|Fungal]] |
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|Opening pressure |
|Opening pressure |
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Latest revision as of 15:46, 11 November 2025
Background
- Inflammation or infection of the meninges and subarachnoid spact
- May be acute, subacute, or chronic (≥4 weeks)
- May be caused by bacteria, viruses, fungi, parasites, or non-infectious causes
- See also aseptic meningitis
Diagnosis
- Typically confirmed by lumbar puncture demonstrating pleocytosis, with or without MRI brain
| Parameter | Normal | Bacterial | Viral | Tuberculous | Fungal |
|---|---|---|---|---|---|
| Opening pressure | 12 to 20 cmH2O | raised | normal or raised | raised | raised |
| Appearance | clear | cloudy | clear | clear or cloudy | clear or cloudy |
| WBC count | <5 | >100 | 5 to 100 | 5 to 500 | 5 to 500 |
| Differential | PMN | lymphocyte | lymphocyte | lymphocyte | |
| Protein | 0.4 g/L | high | somewhat high | very high | high |
| Glucose | >2/3 of plasma | very low | normal to low | very low | low |