Recurrent tuberculosis: Difference between revisions

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Created page with "* Recurrence of TB infection, either as relapse of initial infection (around 80% of recurrences in low-endemic settingsCiteRef::vega2021re) or reinfection (more common in regions with endemic TB) * Occurs at a rate of about 2.26 per 100 person years at riskCiteRef::vega2021re * Typically occurs during first 2 years ** Relapses in susceptible TB mostly occur during first 6 months (78%) and almost always during first 12 months (91%) of therapy[[CiteRef::nunn2010ti]..."
 
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* Typically occurs during first 2 years
* Typically occurs during first 2 years
** Relapses in susceptible TB mostly occur during first 6 months (78%) and almost always during first 12 months (91%) of therapy[[CiteRef::nunn2010ti]]
** Relapses in susceptible TB mostly occur during first 6 months (78%) and almost always during first 12 months (91%) of therapy[[CiteRef::nunn2010ti]]
* Risk factors include multidrug resistance, previous use of fixed-dose combination TB drugs, and poor previous adherence[[CiteRef::vega2024ri]]


[[Category:Tuberculosis]]
[[Category:Tuberculosis]]

Latest revision as of 03:29, 19 September 2025

  • Recurrence of TB infection, either as relapse of initial infection (around 80% of recurrences in low-endemic settings1) or reinfection (more common in regions with endemic TB)
  • Occurs at a rate of about 2.26 per 100 person years at risk1
  • Typically occurs during first 2 years
    • Relapses in susceptible TB mostly occur during first 6 months (78%) and almost always during first 12 months (91%) of therapy2
  • Risk factors include multidrug resistance, previous use of fixed-dose combination TB drugs, and poor previous adherence3

References

  1. a b  Victor Vega, Sharon Rodríguez, Patrick Van der Stuyft, Carlos Seas, Larissa Otero. Recurrent TB: a systematic review and meta-analysis of the incidence rates and the proportions of relapses and reinfections. Thorax. 2021;76(5):494-502. doi:10.1136/thoraxjnl-2020-215449.
  2. ^ nunn2010ti