Tryptase: Difference between revisions
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Created page with "* Serum tryptase is a laboratory test used to investigate suspected anaphylaxis * Acute elevation suggests mast cell degranulation, either IgE-mediated or directly * Rises within minutes of onset of anaphylaxis, and reverts to normal within 6 to 24 hours ** Height of increase often correlates to severity of anaphylaxis * NICE guidelines in the UK recommend taking a sample as soon as possible, with a second sample within 1 to 2 hours of onset of symptoms (no later than 4..." |
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Revision as of 14:36, 29 July 2025
- Serum tryptase is a laboratory test used to investigate suspected anaphylaxis
- Acute elevation suggests mast cell degranulation, either IgE-mediated or directly
- Rises within minutes of onset of anaphylaxis, and reverts to normal within 6 to 24 hours
- Height of increase often correlates to severity of anaphylaxis
- NICE guidelines in the UK recommend taking a sample as soon as possible, with a second sample within 1 to 2 hours of onset of symptoms (no later than 4 hours)
