Coagulase-negative staphylococci: Difference between revisions
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* Group of [[Stain::Gram-positive]] [[ |
* Group of [[Stain::Gram-positive]] [[Shape::coccus|cocci]] that are catalase [[Catalase::positive]] and coagulase [[Coagulase::negative]] |
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==Organisms== |
==Organisms== |
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*'' |
*''Staphylococcus epidermidis'' group |
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** |
**[[Staphylococcus epidermidis]] |
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** |
**[[Staphylococcus capitis]] |
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** |
**[[Staphylococcus simulans]] |
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*''Staphylococcus haemolyticus'' group |
*''Staphylococcus haemolyticus'' group |
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** |
**[[Staphylococcus haemolyticus]] |
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** |
**[[Staphylococcus hominis]] |
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** |
**[[Staphylococcus devriesei]] |
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* |
*[[Staphylococcus saprophyticus]]: mainly causes UTIs |
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* |
*[[Staphylococcus massiliensis]] |
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* |
*[[Staphylococcus lugdenensis]]: has more in common with Staphylococcus aureus and should never be considered a contaminant |
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*Unclear grouping |
*Unclear grouping |
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** |
**[[Staphylococcus lyticans]] |
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** |
**[[Staphylococcus pettenkoferi]] |
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** |
**[[Staphylococcus petrasii]] |
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** |
**[[Staphylococcus pseudolugdunensis]] |
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== Clinical Manifestations == |
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* Common [[Blood culture contamination|contaminants of blood culture bottles]] |
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* Infections more commonly of indwelling hardware |
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* Endocarditis occasionally, and the highest risk is with [[Staphylococcus epidermidis]] than with other species[[CiteRef::ramos-martínez2023ri]][[CiteRef::haddad2023bl]] |
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==Management== |
==Management== |
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*Generally resistant to |
*Generally resistant to [[β-lactams]] |
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*First-line: vancomycin |
*First-line: [[vancomycin]] |
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*Alternatives: linezolid, daptomycin, |
*Alternatives: [[linezolid]], [[daptomycin]], [[co-trimoxazole]], [[ciprofloxacin]], [[doxycycline]] |
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[[Category:Gram-positive cocci]] |
[[Category:Gram-positive cocci]] |
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Latest revision as of 18:18, 30 June 2025
- Group of Gram-positive cocci that are catalase positive and coagulase negative
Organisms
- Staphylococcus epidermidis group
- Staphylococcus haemolyticus group
- Staphylococcus saprophyticus: mainly causes UTIs
- Staphylococcus massiliensis
- Staphylococcus lugdenensis: has more in common with Staphylococcus aureus and should never be considered a contaminant
- Unclear grouping
Clinical Manifestations
- Common contaminants of blood culture bottles
- Infections more commonly of indwelling hardware
- Endocarditis occasionally, and the highest risk is with Staphylococcus epidermidis than with other species12
Management
- Generally resistant to β-lactams
- First-line: vancomycin
- Alternatives: linezolid, daptomycin, co-trimoxazole, ciprofloxacin, doxycycline
References
- ^ Antonio Ramos-Martínez, Patricia González-Merino, Elena Suanzes-Martín, Marta Murga-de la Fuente, Gabriela Escudero-López, Ane Andrés-Eisenhofer, Esther Expósito-Palomo, Andrea Gutierrez-Villanueva, Itziar Diego-Yagüe, Elena Múñez, Ana Fernandez-Cruz, Jorge Calderón-Parra. Risk of endocarditis among patients with coagulase-negative Staphylococcus bacteremia. Scientific Reports. 2023;13(1). doi:10.1038/s41598-023-41888-7.
