Coagulase-negative staphylococci: Difference between revisions
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* Group of [[Stain::Gram-positive]] [[Shape::coccus|cocci]] that are catalase [[Catalase::positive]] and coagulase [[Coagulase::negative]] |
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= Coagulase-negative Staphylococci (CoNS/CNSt) = |
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==Organisms== |
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*''Staphylococcus epidermidis'' group |
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**[[Staphylococcus epidermidis]] |
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**[[Staphylococcus capitis]] |
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**[[Staphylococcus simulans]] |
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** ?''S. warneri'' |
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**[[Staphylococcus haemolyticus]] |
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**[[Staphylococcus hominis]] |
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**[[Staphylococcus devriesei]] |
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** ''S. hominis'' |
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** ''S. devriesei'' |
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**[[Staphylococcus lyticans]] |
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** ''S. lyticans'' |
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**[[Staphylococcus petrasii]] |
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** ''S. petrasii'' |
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**[[Staphylococcus warneri]] |
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== Clinical Manifestations == |
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* Common [[Blood culture contamination|contaminants of blood culture bottles]] |
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* Infections more commonly of indwelling hardware |
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* Endocarditis occasionally, and the highest risk is with [[Staphylococcus epidermidis]] than with other species[[CiteRef::ramos-martínez2023ri]][[CiteRef::haddad2023bl]] |
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==Management== |
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[[Category:Gram-positive cocci]] |
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Latest revision as of 18:18, 30 June 2025
- Group of Gram-positive cocci that are catalase positive and coagulase negative
Organisms
- Staphylococcus epidermidis group
- Staphylococcus haemolyticus group
- Staphylococcus saprophyticus: mainly causes UTIs
- Staphylococcus massiliensis
- Staphylococcus lugdenensis: has more in common with Staphylococcus aureus and should never be considered a contaminant
- Unclear grouping
Clinical Manifestations
- Common contaminants of blood culture bottles
- Infections more commonly of indwelling hardware
- Endocarditis occasionally, and the highest risk is with Staphylococcus epidermidis than with other species12
Management
- Generally resistant to β-lactams
- First-line: vancomycin
- Alternatives: linezolid, daptomycin, co-trimoxazole, ciprofloxacin, doxycycline
References
- ^ Antonio Ramos-Martínez, Patricia González-Merino, Elena Suanzes-Martín, Marta Murga-de la Fuente, Gabriela Escudero-López, Ane Andrés-Eisenhofer, Esther Expósito-Palomo, Andrea Gutierrez-Villanueva, Itziar Diego-Yagüe, Elena Múñez, Ana Fernandez-Cruz, Jorge Calderón-Parra. Risk of endocarditis among patients with coagulase-negative Staphylococcus bacteremia. Scientific Reports. 2023;13(1). doi:10.1038/s41598-023-41888-7.
