Macrocytic anemia: Difference between revisions
From IDWiki
Content deleted Content added
Created page with "== Background == * Anemia with elevated mean corpuscular volume (MCV) above 100 fL == Etiologies == * Megaloblastic (hypersegmented neutrophils suggesting impaired DNA synthesis) ** Vitamin B12 deficiency ** Folate deficiency ** Methotrexate effect * Non-megaloblastic ** Alcohol consumption ** Hereditary spherocytosis ** Hypothyroidism ** Liver disease ** Reticulocytosis from bleeding or hemolysis * May be seen in infants, patients with Dow..." |
(No difference)
|
Revision as of 19:01, 20 June 2025
Background
- Anemia with elevated mean corpuscular volume (MCV) above 100 fL
Etiologies
- Megaloblastic (hypersegmented neutrophils suggesting impaired DNA synthesis)
- Non-megaloblastic
- Alcohol consumption
- Hereditary spherocytosis
- Hypothyroidism
- Liver disease
- Reticulocytosis from bleeding or hemolysis
- May be seen in infants, patients with Down syndrome, and pregnant women
- Extreme macrocytosis greater than 130 fL is sometimes seen with zidovudine, stavudine, and lamivudine
