Immunization of people with asplenia and hyposplenia: Difference between revisions

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*Can receive all routine vaccines, including live vaccines
*Can receive all routine vaccines, including live vaccines
*Try to complete vaccines at least 2 weeks before splenectomy, or wait at least 2 weeks after vaccination to start
*Try to complete vaccines at least 2 weeks before splenectomy, or wait at least 2 weeks after splenectomy to start
*Vaccines specifically recommended in asplenia or hyposplenia:
*Vaccines specifically recommended in asplenia or hyposplenia:
**''Haemophilus influenzae'' type b (Hib), one dose
**''[[Haemophilus influenzae]]'' type b (Hib), one dose
**''Neisseria meningitidis'':
**[[Neisseria meningitidis]]
***Quadrivalent Men-C-ACYW-135, two doses 8 weeks apart followed by a booster every 5 years
***Quadrivalent Men-C-ACYW-135, two doses 8 weeks apart followed by a booster every 5 years
***4CMenB, two doses 4 weeks apart
***4CMenB, two doses 4 weeks apart
**''Streptococcus pneumoniae'':
**[[Streptococcus pneumoniae]]
***Pneu-C-13, one dose with a booster at 5 years. Must wait at least 1 year after Pneu-P-23.
***Pneu-C-20, one dose with a booster at 5 years. Must wait at least 1 year after Pneu-P-23.
⚫
**[[Influenza virus|Influenza]] (annually)
***Pneu-P-23, one dose. Must wait at least 8 weeks after Pneu-C-13.
⚫
**If transfusion-dependent: [[Hepatitis A virus|hepatitis A]] and [[Hepatitis B virus|hepatitis B]] vaccines
⚫
**Influenza (annually)
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**If transfusion-dependent: hepatitis A and B vaccines
*Should also have pill-in-pocket broad-spectrum oral antibiotics to be taken in case of fever
*Should also have pill-in-pocket broad-spectrum oral antibiotics to be taken in case of fever


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|4CMenB
|4CMenB
|4CMenB
|4CMenB
⚫
|
|Pneu-C-13 booster at 5 years
|-
|-
|Pneu-C-13
|Pneu-C-20
| rowspan="2" |
|Pneu-P-23
⚫
|
⚫
|annual influenza vaccination
|-
|-
|Hib
|Hib
⚫
|
|
|
|-
|-
| colspan="2" |influenza, if appropriate season
| colspan="2" |influenza, if appropriate season
⚫
|annual influenza vaccination
⚫
|
|}
|}


Latest revision as of 20:30, 25 February 2025

  • Can receive all routine vaccines, including live vaccines
  • Try to complete vaccines at least 2 weeks before splenectomy, or wait at least 2 weeks after splenectomy to start
  • Vaccines specifically recommended in asplenia or hyposplenia:
  • Should also have pill-in-pocket broad-spectrum oral antibiotics to be taken in case of fever
Sample schedule for vaccination before planned splenectomy
Week -10 Week -2 Week 0 Ongoing
Men-C-ACYW-135 Men-C-ACYW-135 splenectomy Men-C-ACYW-135 booster every 5 years
4CMenB 4CMenB
Pneu-C-20
Hib
influenza, if appropriate season annual influenza vaccination

Further Reading

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