Immunization of people with asplenia and hyposplenia: Difference between revisions

Latest revision as of 20:30, 25 February 2025

Can receive all routine vaccines, including live vaccines
Try to complete vaccines at least 2 weeks before splenectomy, or wait at least 2 weeks after splenectomy to start
Vaccines specifically recommended in asplenia or hyposplenia:
- Haemophilus influenzae type b (Hib), one dose
- Neisseria meningitidis
  - Quadrivalent Men-C-ACYW-135, two doses 8 weeks apart followed by a booster every 5 years
  - 4CMenB, two doses 4 weeks apart
- Streptococcus pneumoniae
  - Pneu-C-20, one dose with a booster at 5 years. Must wait at least 1 year after Pneu-P-23.
- Influenza (annually)
- If transfusion-dependent: hepatitis A and hepatitis B vaccines
Should also have pill-in-pocket broad-spectrum oral antibiotics to be taken in case of fever

Sample schedule for vaccination before planned splenectomy
Week -10	Week -2	Week 0	Ongoing
Men-C-ACYW-135	Men-C-ACYW-135	splenectomy	Men-C-ACYW-135 booster every 5 years
4CMenB	4CMenB
Pneu-C-20
Hib
influenza, if appropriate season			annual influenza vaccination

@@ Line 1: / Line 1: @@
 *Can receive all routine vaccines, including live vaccines
-*Try to complete vaccines at least 2 weeks before splenectomy, or wait at least 2 weeks after vaccination to start
+*Try to complete vaccines at least 2 weeks before splenectomy, or wait at least 2 weeks after splenectomy to start
 *Vaccines specifically recommended in asplenia or hyposplenia:
-**''Haemophilus influenzae'' type b (Hib), one dose
+**''[[Haemophilus influenzae]]'' type b (Hib), one dose
-**''Neisseria meningitidis'':
+**[[Neisseria meningitidis]]
-***Quadrivalent Men-C-ACYW-135, two doses 8 weeks apart
+***Quadrivalent Men-C-ACYW-135, two doses 8 weeks apart followed by a booster every 5 years
 ***4CMenB, two doses 4 weeks apart
-**''Streptococcus pneumoniae'': Pneu-C-13, one dose, followed in 8 weeks by Pneu-P-23, one dose
+**[[Streptococcus pneumoniae]]
+***Pneu-C-20, one dose with a booster at 5 years. Must wait at least 1 year after Pneu-P-23.
-**Influenza (annually)
+**[[Influenza virus|Influenza]] (annually)
-**If transfusion-dependent: hepatitis A and B vaccines
+**If transfusion-dependent: [[Hepatitis A virus|hepatitis A]] and [[Hepatitis B virus|hepatitis B]] vaccines
 *Should also have pill-in-pocket broad-spectrum oral antibiotics to be taken in case of fever
@@ Line 16: / Line 17: @@
 !Week -2
 !Week 0
+!Ongoing
 |-
 |Men-C-ACYW-135
 |Men-C-ACYW-135
 | rowspan="5" |splenectomy
+|Men-C-ACYW-135 booster every 5 years
 |-
 |4CMenB
 |4CMenB
+|
 |-
-|Pneu-C-13
+|Pneu-C-20
+| rowspan="2" |
-|Pneu-P-23
+|
 |-
 |Hib
@@ Line 31: / Line 36: @@
 |-
 | colspan="2" |influenza, if appropriate season
+|annual influenza vaccination
 |}
+== Further Reading ==
+* [https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-3-vaccination-specific-populations/page-7-immunization-persons-with-chronic-diseases.html#p3c6a2 Canadian Immunization Guide: Asplenia or hyposplenia]
 [[Category:Immunocompromised hosts‏‎]]
 [[Category:Vaccination]]