Gardnerella vaginalis: Difference between revisions
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Gardnerella vaginalis
(Created page with "{{DISPLAYTITLE:''Gardnerella vaginalis''}} == Background == * Gram-negative bacillus == Clinical Manifestations == * Involved in bacterial vaginosis, a dysbiosis rather than infection * Rare cause of other infections, including urinary tract infection == Management == * Bacterial vaginosis (a dysbiosis rather than infection) is usually treated with metronidazole, which helps to normalize the overall vaginal microbiome rather than treating the ''Gardnere...") |
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== Background == |
== Background == |
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* Gram-negative bacillus |
* [[Stain::Gram-negative]] or [[Stain::Gram-variable]] [[Shape::bacillus]] or [[Shape::coccobacillus]] |
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* Member of vaginal flora |
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== Clinical Manifestations == |
== Clinical Manifestations == |
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* [[Bacterial vaginosis]] (a dysbiosis rather than infection) is usually treated with [[metronidazole]], which helps to normalize the overall vaginal microbiome rather than treating the ''Gardnerella'' |
* [[Bacterial vaginosis]] (a dysbiosis rather than infection) is usually treated with [[metronidazole]], which helps to normalize the overall vaginal microbiome rather than treating the ''Gardnerella'' |
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* Very little information about antibiotic susceptibility that would be relevant for treating infections |
* Very little information about antibiotic susceptibility that would be relevant for treating infections |
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** Based on one Brazilian study, ampicillin/sulbactam, clindamycin, chloramphenicol are likely reliable; ampicillin and metronidazole are not |
** Based on one Brazilian study, ampicillin/sulbactam, clindamycin, chloramphenicol are likely reliable; ampicillin and metronidazole are not[[CiteRef::knupp de souza2016an]] |
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** A case series reports treatment with ceftriaxone, cefuroxime, aminoglycosides, metronidazole, ciprofloxacin |
** A case series reports treatment with ceftriaxone, cefuroxime, aminoglycosides, metronidazole, ciprofloxacin[[CiteRef::akamine2022ga]] |
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Latest revision as of 18:10, 19 September 2024
Background
- Gram-negative or Gram-variable bacillus or coccobacillus
- Member of vaginal flora
Clinical Manifestations
- Involved in bacterial vaginosis, a dysbiosis rather than infection
- Rare cause of other infections, including urinary tract infection
Management
- Bacterial vaginosis (a dysbiosis rather than infection) is usually treated with metronidazole, which helps to normalize the overall vaginal microbiome rather than treating the Gardnerella
- Very little information about antibiotic susceptibility that would be relevant for treating infections
References
- ^ Daniele Maria Knupp de Souza, Claudio Galuppo Diniz, Didier Silveira Castellano Filho, Laura Maria Andrade de Oliveira, Débora Martins Coelho, Luciana de Souza Talha, Thiago César do Nascimento, Alessandra Barbosa Ferreira-Machado, Vânia Lúcia da Silva. Antimicrobial susceptibility and vaginolysin in Gardnerella vaginalis from healthy and bacterial vaginosis diagnosed women. The Journal of Infection in Developing Countries. 2016;10(09):913-919. doi:10.3855/jidc.7161.
- ^ Christine M Akamine, Andrew Chou, Shahriar Tavakoli-Tabasi, Daniel M Musher. Gardnerella vaginalis Bacteremia in Male Patients: A Case Series and Review of the Literature. Open Forum Infectious Diseases. 2022;9(10). doi:10.1093/ofid/ofac176.
