Ibrutinib: Difference between revisions

From IDWiki
(Created page with "* Bruton's tyrosine kinase inhibitor (important for B cell function) * Used to treat CLL * Increased risk of invasive fungal infections, especially invasive aspergillosis (inc...")
 
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:
* Bruton's tyrosine kinase inhibitor (important for B cell function)
* Bruton's tyrosine kinase inhibitor (important for B cell function)
* Used to treat CLL
* Used to treat CLL
* Can cause [[neutropenia]]
* Increased risk of invasive fungal infections, especially invasive aspergillosis (including CNS disease) [[CiteRef::ghez2018ea]]
* Increased risk of pneumonia, [[UTI]], upper respiratory tract infection, and invasive fungal infections, especially invasive [[aspergillosis]] (including CNS disease) and also [[cryptococcosis]] [[CiteRef::ghez2018ea]]
[[Category:Medications]]
[[Category:Oncology]]
[[Category:Hematology]]

Latest revision as of 17:49, 5 July 2024

  • Bruton's tyrosine kinase inhibitor (important for B cell function)
  • Used to treat CLL
  • Can cause neutropenia
  • Increased risk of pneumonia, UTI, upper respiratory tract infection, and invasive fungal infections, especially invasive aspergillosis (including CNS disease) and also cryptococcosis 1

References

  1. ^  David Ghez, Anne Calleja, Caroline Protin, Marine Baron, Marie-Pierre Ledoux, Gandhi Damaj, Mathieu Dupont, Brigitte Dreyfus, Emmanuelle Ferrant, Charles Herbaux, Kamel Laribi, Ronan Le Calloch, Marion Malphettes, Franciane Paul, Laetitia Souchet, Malgorzata Truchan-Graczyk, Karen Delavigne, Caroline Dartigeas, Loïc Ysebaert. Early-onset invasive aspergillosis and other fungal infections in patients treated with ibrutinib. Blood. 2018;131(17):1955-1959. doi:10.1182/blood-2017-11-818286.