Aerococcus: Difference between revisions
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Aerococcus
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* [[Stain::Gram-positive]] [[Shape::coccus]] |
* [[Stain::Gram-positive]] [[Shape::coccus]] |
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* Notable species |
* Notable species |
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** |
** [[Aerococcus urinae]], which causes urinary tract infections |
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** |
** [[Aerococcus sanguinicola]], causes UTIs, but sometimes a contaminant |
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** |
** [[Aerococcus viridans]], often a contaminant |
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* Presumed resistance ''in vivo'' to [[TMP-SMX]], even though it may appear susceptible ''in vitro'' |
* Presumed resistance ''in vivo'' to [[TMP-SMX]], even though it may appear susceptible ''in vitro'' |
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** It can acquire folate from the host's urine, counteracting the antibiotic |
** It can acquire folate from the host's urine, counteracting the antibiotic |
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== Management == |
== Management == |
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* Penicillin |
* [[Penicillin]] or [[ampicillin]] |
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* ± [[aminoglycoside]] (for synergy, based on in vitro studies) |
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* Can be susceptible to [[ceftriaxone]], though MICs are higher than for [[penicillin]] |
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== Further Reading == |
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{{DISPLAYTITLE:''Aerococcus'' species}} |
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* ''Aerococcus'': an increasingly acknowledged human pathogen. ''Clin Microbiol Infect''. 2016 Jan;22(1):22-27. doi: [https://doi.org/10.1016/j.cmi.2015.09.026 10.1016/j.cmi.2015.09.026]. PMID: [https://pubmed.ncbi.nlm.nih.gov/26454061/ 26454061].{{DISPLAYTITLE:''Aerococcus''}} |
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[[Category:Gram-positive cocci]] |
[[Category:Gram-positive cocci]] |
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Latest revision as of 18:10, 21 June 2024
Microbiology
- Gram-positive coccus
- Notable species
- Aerococcus urinae, which causes urinary tract infections
- Aerococcus sanguinicola, causes UTIs, but sometimes a contaminant
- Aerococcus viridans, often a contaminant
- Presumed resistance in vivo to TMP-SMX, even though it may appear susceptible in vitro
- It can acquire folate from the host's urine, counteracting the antibiotic
Clinical Manifestations
- A. urinae causes UTI and endocarditis (often following UTI in older men)
Management
- Penicillin or ampicillin
- ± aminoglycoside (for synergy, based on in vitro studies)
- Can be susceptible to ceftriaxone, though MICs are higher than for penicillin
Further Reading
- Aerococcus: an increasingly acknowledged human pathogen. Clin Microbiol Infect. 2016 Jan;22(1):22-27. doi: 10.1016/j.cmi.2015.09.026. PMID: 26454061.
