Aerococcus: Difference between revisions

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Aerococcus
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== Microbiology ==
 
== Microbiology ==
   
* Gram-positive coccus
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* [[Stain::Gram-positive]] [[Shape::coccus]]
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* Notable species
* Species that cause disease in humans includes:
 
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** [[Aerococcus urinae]], which causes urinary tract infections
** ''A. urinae''
 
** ''A. sanguinicola''
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** [[Aerococcus sanguinicola]], causes UTIs, but sometimes a contaminant
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** [[Aerococcus viridans]], often a contaminant
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* Presumed resistance ''in vivo'' to [[TMP-SMX]], even though it may appear susceptible ''in vitro''
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** It can acquire folate from the host's urine, counteracting the antibiotic
   
== Clinical Presentation ==
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== Clinical Manifestations ==
   
 
* ''A. urinae'' causes [[UTI]] and [[endocarditis]] (often following UTI in older men)
 
* ''A. urinae'' causes [[UTI]] and [[endocarditis]] (often following UTI in older men)
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== Management ==
 
== Management ==
   
* Penicillin ± aminoglycoside
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* [[Penicillin]] or [[ampicillin]]
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* ± [[aminoglycoside]] (for synergy, based on in vitro studies)
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* Can be susceptible to [[ceftriaxone]], though MICs are higher than for [[penicillin]]
   
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== Further Reading ==
{{DISPLAYTITLE:''Aerococcus'' species}}
 
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* ''Aerococcus'': an increasingly acknowledged human pathogen. ''Clin Microbiol Infect''. 2016 Jan;22(1):22-27. doi: [https://doi.org/10.1016/j.cmi.2015.09.026 10.1016/j.cmi.2015.09.026]. PMID: [https://pubmed.ncbi.nlm.nih.gov/26454061/ 26454061].{{DISPLAYTITLE:''Aerococcus''}}
 
[[Category:Gram-positive cocci]]
 
[[Category:Gram-positive cocci]]

Latest revision as of 14:10, 21 June 2024

Microbiology

  • Gram-positive coccus
  • Notable species
  • Presumed resistance in vivo to TMP-SMX, even though it may appear susceptible in vitro
    • It can acquire folate from the host's urine, counteracting the antibiotic

Clinical Manifestations

Management

Further Reading