Amoxicillin-clavulanic acid: Difference between revisions

From IDWiki
mNo edit summary
No edit summary
 
Line 2: Line 2:
* Oral: 500 mg/125 mg p.o. three times daily, or 875 mg/125 mg p.o. twice daily
* Oral: 500 mg/125 mg p.o. three times daily, or 875 mg/125 mg p.o. twice daily
* Intravenous:
* Intravenous:
** Usual dose: 1 g (1.2 g) IV every 8 hours
** Usual dose: 1 g (1000 mg/ 200 mg) IV every 8 hours
** High dose: 2 g (2.2 g) IV every 8 to 12 hours
** High dose: 2 g (2000 mg/ 200 mg) IV every 8 to 12 hours


=== Renal Dosing ===
=== Renal Dosing ===

Latest revision as of 19:21, 23 June 2023

Dosing

  • Oral: 500 mg/125 mg p.o. three times daily, or 875 mg/125 mg p.o. twice daily
  • Intravenous:
    • Usual dose: 1 g (1000 mg/ 200 mg) IV every 8 hours
    • High dose: 2 g (2000 mg/ 200 mg) IV every 8 to 12 hours

Renal Dosing

CrCl (mL/min) Dose
Oral
>30 875/125 mg p.o. q12h
10-29 500/125 mg p.o. q12h
<10 500/125 mg p.o. q24h
Hemodialysis 500/125 mg p.o. q24h (given after dialysis on dialysis days)
Peritoneal dialysis 250/125 mg p.o. q12h
CRRT Usual dose
Intravenous
>30 1 g IV q8h
10-29 1 g IV followed by 500 mg IV q12h
<10 1 g IV followed by 500 mg IV q24h
Hemodialysis 1 g IV followed by 500 mg IV q24h (given after dialysis on dialysis days)