Thiamine deficiency: Difference between revisions

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(Created page with "* Deficiency of vitamin B1 * Deficiency can cause: ** Wernicke encephalopathy ** Beriberi Category:Gastroenterology")
 
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== Background ==
 
* Deficiency of vitamin B1
 
* Deficiency of vitamin B1
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* Risk factors include:
* Deficiency can cause:
 
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** Weight loss surgery
** [[Wernicke encephalopathy]]
 
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** Total parenteral nutrition, it inadequate thiamine
** [[Beriberi]]
 
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** Alcohol use disorder
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== Clinical Manifestations ==
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* [[Wernicke encephalopathy]], with an acute syndrome characterized by confusion, nystagmus, ataxia, and ophthalmoplegia
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* [[Korsakoff syndrome]], with impaired shot-term memory and confabulation but otherwise normal cognition
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* [[Infantile beriberi]]
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* [[Adult beriberi]]
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** May be "dry", with symmetrical peripheral sensorimotor neuropathy
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** May be "wet", with cardiomegaly and heart failure, in addition to neuropathy
   
 
[[Category:Gastroenterology]]
 
[[Category:Gastroenterology]]

Latest revision as of 12:16, 14 July 2024

Background

  • Deficiency of vitamin B1
  • Risk factors include:
    • Weight loss surgery
    • Total parenteral nutrition, it inadequate thiamine
    • Alcohol use disorder

Clinical Manifestations

  • Wernicke encephalopathy, with an acute syndrome characterized by confusion, nystagmus, ataxia, and ophthalmoplegia
  • Korsakoff syndrome, with impaired shot-term memory and confabulation but otherwise normal cognition
  • Infantile beriberi
  • Adult beriberi
    • May be "dry", with symmetrical peripheral sensorimotor neuropathy
    • May be "wet", with cardiomegaly and heart failure, in addition to neuropathy