Duffy-null associated neutrophil count: Revision history

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    2 November 2022

    • curprev 16:2916:29, 2 November 2022Aidan talk contribs 519 bytes +519 Created page with "== Background == * Previously known as benign ethnic neutropenia * Polymorphisms in ACKR1 gene, which encodes Duffy antigen receptor for chemokines (DARC) * The mutations lead to neutrophils leaving circulation for tissue, resulting in lower peripheral blood neutrophil counts * The gene mutation is present in about 60 to 70% of people with African ancestry, and may have evolved to impair entry of Plasmodium vivax into RBCs * About 10% of people with DANC will have a..." Tag: Visual edit