Urinary tract infection - Revision history

Aidan: added CRE

2022-08-30T12:55:18Z

added CRE

@@ Line 76: / Line 76: @@
 ** Preferred: [[ertapenem]], [[meropenem]], [[imipenem-cilastatin]], [[ciprofloxacin]], [[levofloxacin]], or [[trimethoprim-sulfamethoxazole]]
 ** Alternatives: once-daily [[aminoglycosides]]
 [[Category:Genitourinary infections]]

Aidan at 12:49, 30 August 2022

2022-08-30T12:49:37Z

← Older revision		Revision as of 12:49, 30 August 2022
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	*** [[Ciprofloxacin]] XR 500 mg p.o. daily for 3 days		*** [[Ciprofloxacin]] XR 500 mg p.o. daily for 3 days
	*** [[Levofloxacin]] 250 mg p.o. daily for 3 days		*** [[Levofloxacin]] 250 mg p.o. daily for 3 days

			=== ESBLs ===

			* Uncomplicated UTIs:
			** Preferred: [[nitrofurantoin]] or [[co-trimoxazole]]
			** Alternatives: [[amoxicillin-clavulanate]] (if in vitro susceptibility), single-dose [[aminoglycosides]], and oral [[fosfomycin]] (for [[Escherichia coli\|E. coli]])
			* Complicated UTIs and pyelonephritis:
			** Preferred: [[ertapenem]], [[meropenem]], [[imipenem-cilastatin]], [[ciprofloxacin]], [[levofloxacin]], or [[trimethoprim-sulfamethoxazole]]
			** Alternatives: once-daily [[aminoglycosides]]

	[[Category:Genitourinary infections]]		[[Category:Genitourinary infections]]

Aidan at 23:00, 2 August 2022

2022-08-02T23:00:10Z

@@ Line 27: / Line 27: @@
 ==Clinical Manifestations==
 *Diagnostic criteria include clinical and laboratory symptoms:
 **Two or more clinical symptoms:
@@ Line 50: / Line 52: @@
 * Acute afebrile UTI in men: 7 days [[ciprofloxacin]] or [[cotrimoxazole]][[CiteRef::drekonja2021ef]]
 [[Category:Genitourinary infections]]

Aidan at 12:08, 1 August 2022

2022-08-01T12:08:13Z

← Older revision		Revision as of 12:08, 1 August 2022
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	* '''Premenopausal women:''' sexual intercourse, new partner, no postcoital voiding, spermicide use, prior UTI, [[diabetes mellitus]]		* '''Premenopausal women:''' sexual intercourse, new partner, no postcoital voiding, spermicide use, prior UTI, [[diabetes mellitus]]
	* '''Postmenopausal women:''' estrogen deficiency, incontinence, postvoid residual, catheterization		* '''Postmenopausal women:''' genitourinary atrophy/estrogen deficiency, urethral diverticulum, vaginal prolapse beyond the hymen, incontinence, postvoid residual, catheterization
	* '''Men:''' reduced prostatic secretions (older men), postvoid residual, incontinence, catheterization		* '''Men:''' reduced prostatic secretions (older men), postvoid residual, incontinence, catheterization

Aidan at 01:27, 22 December 2021

2021-12-22T01:27:51Z

← Older revision		Revision as of 01:27, 22 December 2021
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	*Urine microscopy		*Urine microscopy
	**Pyuria indicated by 5-10 cells per HPF		**Pyuria indicated by 5-10 cells per HPF

			== Management ==

			* Acute afebrile UTI in men: 7 days [[ciprofloxacin]] or [[cotrimoxazole]][[CiteRef::drekonja2021ef]]

	[[Category:Genitourinary infections]]		[[Category:Genitourinary infections]]

Aidan at 15:45, 24 August 2020

2020-08-24T15:45:45Z

← Older revision		Revision as of 15:45, 24 August 2020
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	== Background ==		==Background==

	*Bacterial infection of the urinary tract, either lower (cystitis) or upper (pyelonephritis)		*Bacterial infection of the urinary tract, either lower (cystitis) or upper (pyelonephritis)
	*When UTI causes sepsis syndrome, often referred to as urosepsis		*When UTI causes sepsis syndrome, often referred to as urosepsis

	=== Microbiology ===		===Microbiology===

			*Gram-negative bacteria
	*Ascending genitourinary infection
	**''[[E. coli]]''		**[[Escherichia coli]], most common cause overall
			**[[Proteus]], [[Klebsiella]], [[Enterobacter]]
	**''[[S. saprophicitus]]''
			**[[Pseudomonas]], [[Acinetobacter]]
			* Gram-positive bacteria
			**[[Staphylococcus saprophyticus]], more common in young women
	**[[Enterococcus faecalis]]		**[[Enterococcus faecalis]]
			**[[Staphylococcus aureus]], as a complication of [[Staphylococcus aureus bacteremia]]
	*Bacteremia
	**[[~~Staphylococcus~~ ~~aureus~~]]		**[[Corynebacterium urealyticum]]
			*Viruses
	**[[Candida species]]
			**[[Adenovirus]], which can cause [[hemorrhagic cystitis]] in [[hematopoietic stem cell transplantation]] recipients
			**[[BK virus]], in renal transplant recipients

			=== Risk Factors ===

			* '''Premenopausal women:''' sexual intercourse, new partner, no postcoital voiding, spermicide use, prior UTI, [[diabetes mellitus]]
			* '''Postmenopausal women:''' estrogen deficiency, incontinence, postvoid residual, catheterization
			* '''Men:''' reduced prostatic secretions (older men), postvoid residual, incontinence, catheterization

	==Clinical Manifestations==		==Clinical Manifestations==
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	==Investigations==		==Investigations==

			*Urinalysis
	*Urinalysis has high NPV (~100%) if negative for leukocyst esterase and nitrites
			**Leukocyte esterase
			**Nitrite, positive for organisms that convert nitrate to nitrite such as the Gram-negative bacteria
			**High negative predictive value if both LE and nitrite are negative
			*Urine microscopy
			**Pyuria indicated by 5-10 cells per HPF

	[[Category:Genitourinary infections]]		[[Category:Genitourinary infections]]

Aidan at 15:28, 24 August 2020

2020-08-24T15:28:21Z

← Older revision		Revision as of 15:28, 24 August 2020
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			== Background ==
⚫	* Bacterial infection of the urinary tract, either lower (cystitis) or upper (pyelonephritis)
⚫	* When UTI causes sepsis syndrome, often referred to as urosepsis

		⚫	*Bacterial infection of the urinary tract, either lower (cystitis) or upper (pyelonephritis)
	== Criteria ==
		⚫	*When UTI causes sepsis syndrome, often referred to as urosepsis

			=== Microbiology ===
⚫	* Diagnostic criteria include clinical and laboratory symptoms:
⚫	** Two or more clinical symptoms:
⚫	*** Fever > 38ºC
⚫	*** Urinary urgency or frequency
⚫	*** Acute dysuria
⚫	*** Hypogastric pain
⚫	*** Costovertebral angle tenderness
⚫	** One or more laboratory finding:
⚫	*** Bacteriuria (> 100,000 CFUs/mL)
⚫	*** Pyuria (>10 WBCs/HPF)

			*Ascending genitourinary infection
	== Etiology ==
		⚫	**''[[E. coli]]''
		⚫	**''[[S. saprophicitus]]''
			**[[Enterococcus faecalis]]
			*Bacteremia
			**[[Staphylococcus aureus]]
			**[[Candida species]]

			==Clinical Manifestations==
	* Typical organisms include:
⚫	** ''[[E. coli]]''
⚫	** ''[[S. saprophicitus]]''

		⚫	*Diagnostic criteria include clinical and laboratory symptoms:
⚫	== Investigations ==
		⚫	**Two or more clinical symptoms:
		⚫	***Fever > 38ºC
		⚫	***Urinary urgency or frequency
		⚫	***Acute dysuria
		⚫	***Hypogastric pain
		⚫	***Costovertebral angle tenderness
		⚫	**One or more laboratory finding:
		⚫	***Bacteriuria (> 100,000 CFUs/mL)
		⚫	***Pyuria (>10 WBCs/HPF)

		⚫	==Investigations==
	* Labs

	** Urinalysis has high NPV (~100%) if negative for leukocyst esterase and nitrites ~~is negative~~		*Urinalysis has high NPV (~100%) if negative for leukocyst esterase and nitrites

	[[Category:Genitourinary infections]]		[[Category:Genitourinary infections]]

Aidan: Aidan moved page Urinary tract infections to Urinary tract infection over redirect

2019-09-05T14:58:11Z

Aidan moved page Urinary tract infections to Urinary tract infection over redirect

← Older revision	Revision as of 14:58, 5 September 2019
(No difference)

Aidan: /* Definition */

2019-09-05T14:41:33Z

Definition

← Older revision		Revision as of 14:41, 5 September 2019
Line 1:		Line 1:
	== Definition ==

	* Bacterial infection of the urinary tract, either lower (cystitis) or upper (pyelonephritis)		* Bacterial infection of the urinary tract, either lower (cystitis) or upper (pyelonephritis)
	* When UTI causes sepsis syndrome, often referred to as urosepsis		* When UTI causes sepsis syndrome, often referred to as urosepsis

			== Criteria ==

	* Diagnostic criteria include clinical and laboratory symptoms:		* Diagnostic criteria include clinical and laboratory symptoms:
	** Two or more clinical symptoms:		** Two or more clinical symptoms:

Aidan: /* Etiology */

2019-08-17T15:31:47Z

Etiology

← Older revision		Revision as of 15:31, 17 August 2019
Line 17:		Line 17:

	* Typical organisms include:		* Typical organisms include:
	** E. coli		** ''[[E. coli]]''
	** S. saprophicitus		** ''[[S. saprophicitus]]''

	== Investigations ==		== Investigations ==