Tick-borne encephalitis virus - Revision history

Aidan: /* Clinical Manifestations */

2023-09-15T15:12:26Z

Clinical Manifestations

← Older revision		Revision as of 15:12, 15 September 2023
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	* Illness begins with non-specific [[Causes::influenza-like illness]], with [[Causes::fever]], [[Causes::malaise]], [[Causes::headache]], [[Causes::nausea]], [[Causes::vomiting]], and [[Causes::myalgias]]		* Illness begins with non-specific [[Causes::influenza-like illness]], with [[Causes::fever]], [[Causes::malaise]], [[Causes::headache]], [[Causes::nausea]], [[Causes::vomiting]], and [[Causes::myalgias]]
	* Initial symptoms resolve within a week, and for most people, nothing further happens		* Initial symptoms resolve within a week, and for most people, nothing further happens
	* In severe disease, however, symptoms return ~~withing~~ 2 to 8 days (range 1 to 20 days), with high fever, headache, and vomiting		* In severe disease, however, symptoms return within 2 to 8 days (range 1 to 20 days), with high fever, headache, and vomiting
	** Spectrum of disease from aseptic meningitis to meningoencephalitis to poliomyelitis-like flaccid paralysis or polyradiculoneuritis Guillain-Barré-like paralysis		** Spectrum of disease from [[aseptic meningitis]] to [[meningoencephalitis]] to poliomyelitis-like flaccid paralysis or polyradiculoneuritis [[Guillain-Barré syndrome\|Guillain-Barré]]-like paralysis
	** Symptoms are most severe in the elderly and mostly mild in children		** Symptoms are most severe in the elderly and mostly mild in children
	* Most severe form is with TBEV-FE, where mortality is about 20% among hospitalized patients and 60% of survivors having neurologic sequelae		* Most severe form is with TBEV-FE, where mortality is about 20% among hospitalized patients and 60% of survivors having neurologic sequelae

Aidan: Text replacement - " species]]" to "]]"

2022-01-27T05:33:08Z

Text replacement - " species]]" to "]]"

← Older revision		Revision as of 05:33, 27 January 2022
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	* Three subtypes, Far Eastern (TBEV-FE), Siberian (TBEV-Sib), and European (TBEV-Eu)		* Three subtypes, Far Eastern (TBEV-FE), Siberian (TBEV-Sib), and European (TBEV-Eu)
	* Greatest number of cases reported in Czech Republic, Lithuania, Latvia, Germany, and Slovenia		* Greatest number of cases reported in Czech Republic, Lithuania, Latvia, Germany, and Slovenia
	* Transmitted by [[Vector::Ixodes ~~species~~]] ticks		* Transmitted by [[Vector::Ixodes]] ticks
	** Also has transovarial and transstadial transmission, and may be transmitted between ticks feeding on the same host		** Also has transovarial and transstadial transmission, and may be transmitted between ticks feeding on the same host
	** Mostly in sheltered microhabitats with high humidity, moderate temperatures, up to 2100 m elevation		** Mostly in sheltered microhabitats with high humidity, moderate temperatures, up to 2100 m elevation
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	\|Far Eastern (TBEV-FE)		\|Far Eastern (TBEV-FE)
	\|eastern Russia, Korea, China, parts of Japan, and parts of the Baltic		\|eastern Russia, Korea, China, parts of Japan, and parts of the Baltic
	\|[[Vector::Ixodes persulcatus]], [[Vector::Ixodes ovatus]] (Japan), [[Vector::Haemaphysalis ~~species~~]] (Korea)		\|[[Vector::Ixodes persulcatus]], [[Vector::Ixodes ovatus]] (Japan), [[Vector::Haemaphysalis]] (Korea)
	\|-		\|-
	\|Siberian (TBEV-Sib)		\|Siberian (TBEV-Sib)

Aidan: Created page with "== Background == * Single-stranded, positive-sense RNA virus in the Flaviviridae family, genus Flavivirus * Three subtypes, Far Eastern (TBEV-FE), Siberian (TBEV-Sib)..."

2020-08-19T14:50:52Z

Created page with "== Background == * Single-stranded, positive-sense RNA virus in the Flaviviridae family, genus Flavivirus * Three subtypes, Far Eastern (TBEV-FE), Siberian (TBEV-Sib)..."

New page

== Background ==

* Single-stranded, positive-sense RNA virus in the [[Flaviviridae]] family, genus [[Flavivirus]]
* Three subtypes, Far Eastern (TBEV-FE), Siberian (TBEV-Sib), and European (TBEV-Eu)
* Greatest number of cases reported in Czech Republic, Lithuania, Latvia, Germany, and Slovenia
* Transmitted by [[Vector::Ixodes species]] ticks
** Also has transovarial and transstadial transmission, and may be transmitted between ticks feeding on the same host
** Mostly in sheltered microhabitats with high humidity, moderate temperatures, up to 2100 m elevation
* Reservoirs include numerous birds and mammal hosts; humans are incidental in the transmission cycle

{| class="wikitable"
!Subtype
!Distribution
!Vector
|-
|Far Eastern (TBEV-FE)
|eastern Russia, Korea, China, parts of Japan, and parts of the Baltic
|[[Vector::Ixodes persulcatus]], [[Vector::Ixodes ovatus]] (Japan), [[Vector::Haemaphysalis species]] (Korea)
|-
|Siberian (TBEV-Sib)
|Russia
|[[Vector::Ixodes persulcatus]]
|-
|European (TBEV-Eu)
|Scandinavia, Europe, and eastern states of the former Soviet Union
|[[Vector::Ixodes ricinus]]
|}

== Clinical Manifestations ==

* Incubation period of [[Usual incubation period::8 days]] (range [[Incubation period range::4 to 28 days]])
* Illness begins with non-specific [[Causes::influenza-like illness]], with [[Causes::fever]], [[Causes::malaise]], [[Causes::headache]], [[Causes::nausea]], [[Causes::vomiting]], and [[Causes::myalgias]]
* Initial symptoms resolve within a week, and for most people, nothing further happens
* In severe disease, however, symptoms return withing 2 to 8 days (range 1 to 20 days), with high fever, headache, and vomiting
** Spectrum of disease from aseptic meningitis to meningoencephalitis to poliomyelitis-like flaccid paralysis or polyradiculoneuritis Guillain-Barré-like paralysis
** Symptoms are most severe in the elderly and mostly mild in children
* Most severe form is with TBEV-FE, where mortality is about 20% among hospitalized patients and 60% of survivors having neurologic sequelae
* Mortality is 6 to 8% for TBEV-Sib and 1-2% for TBEV-Eu

[[Category:Vector-borne infections]]
[[Category:Flaviviridae]]