Aidan: Created page with "== Differential Diagnosis == * Peripheral artery disease * Thromboembolism * Vasculitis * Trauma * Medication effects, including amphetamines and cocaine == Diagnosis == === Clinical Criteria === * Criteria are not universally accepted but include Age less than 50 years (or 45 years) Current or recent tobacco use Ischemia of the distal extremities, documented by vascular testing Typical arteriographic findings, including corksc..."

2022-07-12T13:47:04Z

Created page with "== Differential Diagnosis == * Peripheral artery disease * Thromboembolism * Vasculitis * Trauma * Medication effects, including amphetamines and cocaine == Diagnosis == === Clinical Criteria === * Criteria are not universally accepted but include ** Age less than 50 years (or 45 years) ** Current or recent tobacco use ** Ischemia of the distal extremities, documented by vascular testing ** Typical arteriographic findings, including corksc..."

New page

== Differential Diagnosis ==

* [[Peripheral artery disease]]
* Thromboembolism
* [[Vasculitis]]
* Trauma
* Medication effects, including [[Amphetamine|amphetamines]] and [[cocaine]]

== Diagnosis ==

=== Clinical Criteria ===

* Criteria are not universally accepted but include
** Age less than 50 years (or 45 years)
** Current or recent tobacco use
** Ischemia of the distal extremities, documented by vascular testing
** Typical arteriographic findings, including corkscrew appearance, spider legs, or tree roots
** Exclusion of other causes, including autoimmune diseases, [[thrombophilia]], [[diabetes mellitus]], and thromboembolism

== Investigations ==

* CBC, liver panel, electrolytes, cretinine, HbA1c, lipid panel, urinalysis
* ESR/CRP
* ANA, RF, cryoglobulins, complements, anti-centromere (for [[CREST]]), anti-Scl-70 (for [[scleroderma]]), antiphospholipid antibodies
* Protein C & S, antithrombin III, Factor V Leiden, prothrombin, homocysteinemia
* Toxicology for cocaine and amphetamines
* Ultrasound with segmental arterial Dopplers
* Echocardiography (for embolic source)
* +/- CT (for embolic source)
* Biopsy, maybe

[[Category:Rheumatology]]

Thromboangiitis obliterans - Revision history