Syndrome of inappropriate ADH - Revision history

Aidan: /* Differential Diagnosis */

2026-04-06T14:59:29Z

Differential Diagnosis

← Older revision		Revision as of 14:59, 6 April 2026
Line 17:		Line 17:
	== Differential Diagnosis ==		== Differential Diagnosis ==

			* [[Cerebral salt wasting]]
	* [[Cerebral salt wasting]], which mimics SIADH and is most commonly caused by [[subarachnoid hemorrhage]], but requires fluid resuscitation rather than restriction
			** Mimics SIADH
			** Most commonly caused by [[subarachnoid hemorrhage]]
			** Cerebral salt wasting should have high-normal serum urea, low serum uric acid, high urine volume, high urine sodium, normal to orthostatic blood pressure, and low central venous pressure
			** Requires fluid resuscitation rather than restriction

	== Diagnostic Criteria ==		== Diagnostic Criteria ==

Aidan at 14:07, 6 April 2026

2026-04-06T14:07:26Z

@@ Line 17: / Line 17: @@
 == Differential Diagnosis ==
-* [[Cerebral salt wasting]], which mimics SIADH and is most commonly caused by [[subarachnoid hemorrhage]]
+* [[Cerebral salt wasting]], which mimics SIADH and is most commonly caused by [[subarachnoid hemorrhage]], but requires fluid resuscitation rather than restriction
 [[Category:Nephrology]]

Aidan: Created page with "== Background == === Etiologies === * CNS: stroke, intracranial hemorrhage, infection, trauma, and psychosis * Malignancy: ectopic ADH production by small cell carcinoma or, even more rarely, with other lung cancers, head-and-neck cancer, olfactory neuroblastoma, and extrapulmonary small cell carcinoma * Medications: chlorpropamide, carbamazepine, oxcarbazepine, high-dose cyclophosphamide, SSRIs ** Others: vincristine, [[cinblastine]..."

2023-05-09T13:47:50Z

Created page with "== Background == === Etiologies === * CNS: stroke, intracranial hemorrhage, infection, trauma, and psychosis * Malignancy: ectopic ADH production by small cell carcinoma or, even more rarely, with other lung cancers, head-and-neck cancer, olfactory neuroblastoma, and extrapulmonary small cell carcinoma * Medications: chlorpropamide, carbamazepine, oxcarbazepine, high-dose cyclophosphamide, SSRIs ** Others: vincristine, [[cinblastine]..."

New page

== Background ==

=== Etiologies ===

* CNS: [[stroke]], [[intracranial hemorrhage]], infection, trauma, and psychosis
* Malignancy: ectopic ADH production by [[small cell carcinoma]] or, even more rarely, with other lung cancers, head-and-neck cancer, olfactory neuroblastoma, and extrapulmonary small cell carcinoma
* Medications: [[chlorpropamide]], [[carbamazepine]], [[oxcarbazepine]], high-dose [[cyclophosphamide]], [[SSRIs]]
** Others: [[vincristine]], [[cinblastine]], [[cinorelbine]], [[cisplatin]], [[thiothixene]], [[thioridazine]], [[haloperidol]], [[amitriptyline]], [[MAO inhibitors]], [[melphalan]], [[ifosfamide]], [[methotrexate]], [[opiates]], [[NSAIDs]], [[interferon alpha]], [[interferon gamma]], [[sodium valproate]], [[bromocriptine]], [[lorcainide]], [[amiodarone]], [[ciprofloxacin]], high-dose [[imatinib]], and [[ecstasy]]
* Surgery, likely mediated by pain, but also specifically after transsphenoidal pituitary surgery
* Lung disease: [[pneumonia]], occasionally also with [[asthma]], [[atelectasis]], respiratory failure, and [[pneumothorax]]
* Endocrinopathies: [[hypopituitarism]] and [[hypothyroidism]]
** Also exogenous [[vasopressin]], [[desmopressin]], and [[oxytocin]]
* [[HIV]]
* Hereditary SIADH
* Idiopathy, more common in older patients though occasionally found later to be from occult malignancy

== Differential Diagnosis ==

* [[Cerebral salt wasting]], which mimics SIADH and is most commonly caused by [[subarachnoid hemorrhage]]

[[Category:Nephrology]]
[[Category:Endocrinology]]