Staphylococcus aureus decolonization - Revision history

Aidan: /* Dutch Method */

2021-08-18T12:52:21Z

Dutch Method

← Older revision		Revision as of 12:52, 18 August 2021
Line 4:		Line 4:
	== Project CLEAR ==		== Project CLEAR ==

	* Probably has the best evidence [[CiteRef::huang2019de]]		* Probably has the best evidence, with an RCT[[CiteRef::huang2019de]]
	* Decolonization happens for 5 days, twice monthly, for 6 months		* Decolonization happens for 5 days, twice monthly, for 6 months
	** 4% rinse-off chlorhexidine for daily bathing or showering		** 4% rinse-off chlorhexidine for daily bathing or showering
Line 13:		Line 13:
	== Dutch Method ==		== Dutch Method ==

	* Also has some evidence [[CiteRef::ammerlaan2011er]]		* Also has some evidence, with an observational study[[CiteRef::ammerlaan2011er]]
	* Separates patients into uncomplicated (essentially entirely asymptomatic carriage in a low-risk patient) and complicated		* Separates patients into uncomplicated (essentially entirely asymptomatic carriage in a low-risk patient) and complicated
			* In the above report, the only reported outcome was decolonization
			** 63% after 1 cycle, and 80% after up to 5 cycles of treatment
			** 97% remained decolonized at 3 month follow-up

	=== Uncomplicated carriage ===		=== Uncomplicated carriage ===

2021-08-10T13:20:40Z

Complicated carriage

← Older revision		Revision as of 13:20, 10 August 2021
Line 28:		Line 28:

	* As above, plus oral antibiotics		* As above, plus oral antibiotics
	* [[~~TMP-SMX~~]] (200 mg ~~twice~~ a ~~day)~~ + [[rifampin]] (600 mg twice a day) for 1 week		* [[Trimethoprim]] 200 mg PO BID or [[doxycycline]] 200 mg PO once daily, plus [[rifampin]] 600 mg twice a day for 1 week
			* Alternative: [[clindamycin]] 600 mg PO TID or [[clarithromycin]] 500 mg PO BID or [[ciprofloxacin]] 750 mg PO BID or [[fusidic acid]] 500 mg PO TID, plus [[fusidic acid]] 500 mg PO TID

	{{DISPLAYTITLE:''Staphylococcus aureus'' decolonization}}		{{DISPLAYTITLE:''Staphylococcus aureus'' decolonization}}

2019-09-05T14:13:48Z

Project CLEAR: added line about results

← Older revision		Revision as of 14:13, 5 September 2019
Line 9:		Line 9:
	** 0.12% chlorhexidine mouthwash twice daily		** 0.12% chlorhexidine mouthwash twice daily
	** 2% nasal mupirocin twice daily		** 2% nasal mupirocin twice daily
			* NNT of about 30 to prevent one infection or one hospitalization

	== Dutch Method ==		== Dutch Method ==

2019-09-05T01:17:13Z

← Older revision		Revision as of 01:17, 5 September 2019
Line 1:		Line 1:
			* [[Staphylococcus aureus]] is commonly found in the nares and on the skin of healthy people
			* Asymptomatic colonization is associated with a higher rate of invasive infection

	== Project CLEAR ==		== Project CLEAR ==

2019-09-05T00:27:25Z

Renamed Method 1 to Project CLEAR

← Older revision		Revision as of 00:27, 5 September 2019
Line 1:		Line 1:
	== ~~Method~~ 1 ==		== Project CLEAR ==

	* Probably has the best evidence [[CiteRef::huang2019de]]		* Probably has the best evidence [[CiteRef::huang2019de]]
		⚫	* Decolonization happens for 5 days, twice monthly, for 6 months
	* 4% rinse-off chlorhexidine for daily bathing or showering
	* ~~0.12~~% chlorhexidine ~~mouthwash twice~~ daily		** 4% rinse-off chlorhexidine for daily bathing or showering
	* 2% ~~nasal~~ ~~mupirocin~~ twice daily		** 0.12% chlorhexidine mouthwash twice daily
			** 2% nasal mupirocin twice daily
⚫	* ~~All~~ ~~administered~~ for ~~five~~ days twice ~~per month~~ for ~~six~~ months

	== Dutch Method ==		== Dutch Method ==

2019-09-05T00:17:49Z

added dutch method

@@ Line 6: / Line 6: @@
 * 2% nasal mupirocin twice daily
 * All administered for five days twice per month for six months
 {{DISPLAYTITLE:''Staphylococcus aureus'' decolonization}}

2019-09-05T00:07:47Z

← Older revision		Revision as of 00:07, 5 September 2019
Line 1:		Line 1:
			== Method 1 ==

		⚫	* Probably has the best evidence [[CiteRef::huang2019de]]
	* 4% rinse-off chlorhexidine for daily bathing or showering		* 4% rinse-off chlorhexidine for daily bathing or showering
	* 0.12% chlorhexidine mouthwash twice daily		* 0.12% chlorhexidine mouthwash twice daily
	* 2% nasal mupirocin twice daily		* 2% nasal mupirocin twice daily
	* All administered for five days twice per month for six months		* All administered for five days twice per month for six months

⚫	[[CiteRef::huang2019de]]

	{{DISPLAYTITLE:''Staphylococcus aureus'' decolonization}}		{{DISPLAYTITLE:''Staphylococcus aureus'' decolonization}}

2019-09-05T00:07:14Z

← Older revision		Revision as of 00:07, 5 September 2019
Line 4:		Line 4:
	* All administered for five days twice per month for six months		* All administered for five days twice per month for six months

	~~{{#scite~~:huang2019de}}		[[CiteRef::huang2019de]]

	{{DISPLAYTITLE:''Staphylococcus aureus'' decolonization}}		{{DISPLAYTITLE:''Staphylococcus aureus'' decolonization}}

2019-09-05T00:01:39Z

← Older revision		Revision as of 00:01, 5 September 2019
Line 3:		Line 3:
	* 2% nasal mupirocin twice daily		* 2% nasal mupirocin twice daily
	* All administered for five days twice per month for six months		* All administered for five days twice per month for six months

			{{#scite:huang2019de}}

	{{DISPLAYTITLE:''Staphylococcus aureus'' decolonization}}		{{DISPLAYTITLE:''Staphylococcus aureus'' decolonization}}

2019-09-04T23:59:19Z

← Older revision		Revision as of 23:59, 4 September 2019
Line 1:		Line 1:
			* 4% rinse-off chlorhexidine for daily bathing or showering

			* 0.12% chlorhexidine mouthwash twice daily
			* 2% nasal mupirocin twice daily
			* All administered for five days twice per month for six months

	{{DISPLAYTITLE:''Staphylococcus aureus'' decolonization}}		{{DISPLAYTITLE:''Staphylococcus aureus'' decolonization}}