Spontaneous gram-negative meningitis - Revision history

Aidan at 16:27, 19 July 2023

2023-07-19T16:27:21Z

← Older revision		Revision as of 16:27, 19 July 2023
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	* Most commonly caused by [[Escherichia coli]], [[Klebsiella pneumoniae]], [[Pseudomonas aeruginosa]], and [[Acinetobacter]]		* Most commonly caused by [[Escherichia coli]], [[Klebsiella pneumoniae]], [[Pseudomonas aeruginosa]], and [[Acinetobacter]]
	* Also [[Citrobacter]], [[Serratia marcescens]], [[Enterobacter]], and [[Proteus mirabilis]]		* Also [[Citrobacter]], [[Serratia marcescens]], [[Enterobacter]], and [[Proteus mirabilis]]
			* Typically excludes usual causes of meningitis such as [[Haemophilus]] or [[Neisseria]]

	=== Risk Factors ===		=== Risk Factors ===
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	\|-		\|-
	\|ESBL Gram-negative bacillus\|\|[[meropenem]]\|\|[[cefepime]] or a fluoroquinolone		\|ESBL Gram-negative bacillus\|\|[[meropenem]]\|\|[[cefepime]] or a fluoroquinolone
	\|-
	\|''[[Haemophilus influenzae]]'' (β-lactamase negative)\|\|[[ampicillin]]\|\|third-generation cephalosporin, [[cefepime]], [[chloramphenicol]], or a fluoroquinolone
	\| rowspan="2" \|7 days
	\|-
	\|''[[Haemophilus influenzae]]'' (β-lactamase positive)\|\|third-generation cephalosporin\|\|[[cefepime]], [[chloramphenicol]], or a fluoroquinolone
	\|}		\|}
	[[Category:CNS infections]]		[[Category:CNS infections]]

Aidan at 16:26, 19 July 2023

2023-07-19T16:26:33Z

← Older revision		Revision as of 16:26, 19 July 2023
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	* CNS dosed antibiotics to complete 21 days is typically sufficient		* CNS dosed antibiotics to complete 21 days is typically sufficient
			{\| class="wikitable sortable"

			!Organism
			!First-line
			!Second-line
			!Duration
			\|-
			\|''[[E. coli]]'' and other [[Enterobacteriaceae]]\|\|third-generation cephalosporin\|\|[[ampicillin]], [[meropenem]], [[aztreonam]], [[TMP-SMX]], or [[ciprofloxacin]]
			\| rowspan="3" \|21 days
			\|-
			\|''[[Pseudomonas aeruginosa]]''\|\|[[cefipime]] or [[ceftazidime]]\|\|[[meropenem]], [[aztreonam]], or [[ciprofloxacin]]
			\|-
			\|ESBL Gram-negative bacillus\|\|[[meropenem]]\|\|[[cefepime]] or a fluoroquinolone
			\|-
			\|''[[Haemophilus influenzae]]'' (β-lactamase negative)\|\|[[ampicillin]]\|\|third-generation cephalosporin, [[cefepime]], [[chloramphenicol]], or a fluoroquinolone
			\| rowspan="2" \|7 days
			\|-
			\|''[[Haemophilus influenzae]]'' (β-lactamase positive)\|\|third-generation cephalosporin\|\|[[cefepime]], [[chloramphenicol]], or a fluoroquinolone
			\|}
	[[Category:CNS infections]]		[[Category:CNS infections]]

Aidan at 16:24, 19 July 2023

2023-07-19T16:24:22Z

← Older revision		Revision as of 16:24, 19 July 2023
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	* [[Substance abuse]], including [[alcohol use disorder]]		* [[Substance abuse]], including [[alcohol use disorder]]
	* [[Cancer]]		* [[Cancer]]

			== Clinical Presentation ==

			* As per other forms of [[bacterial meningitis]]

			== Management ==

			* CNS dosed antibiotics to complete 21 days is typically sufficient

	[[Category:CNS infections]]		[[Category:CNS infections]]

Aidan at 14:58, 19 July 2023

2023-07-19T14:58:51Z

← Older revision		Revision as of 14:58, 19 July 2023
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	* Also [[Citrobacter]], [[Serratia marcescens]], [[Enterobacter]], and [[Proteus mirabilis]]		* Also [[Citrobacter]], [[Serratia marcescens]], [[Enterobacter]], and [[Proteus mirabilis]]

	=== Risk ~~Factosr~~ ===		=== Risk Factors ===

	* Diabetes mellitus		* [[Diabetes mellitus]]
	* Cirrhosis		* [[Cirrhosis]]
	* End-stage renal disease		* [[End-stage renal disease]]
	* Substance abuse, including alcohol use disorder		* [[Substance abuse]], including [[alcohol use disorder]]
	* Cancer		* [[Cancer]]

	[[Category:CNS infections]]		[[Category:CNS infections]]

Aidan: Created page with "== Background == === Microbiology === * Most commonly caused by Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter * Also Citrobacter, Serratia marcescens, Enterobacter, and Proteus mirabilis === Risk Factosr === * Diabetes mellitus * Cirrhosis * End-stage renal disease * Substance abuse, including alcohol use disorder * Cancer Category:CNS infections"

2023-07-19T13:53:41Z

Created page with "== Background == === Microbiology === * Most commonly caused by Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter * Also Citrobacter, Serratia marcescens, Enterobacter, and Proteus mirabilis === Risk Factosr === * Diabetes mellitus * Cirrhosis * End-stage renal disease * Substance abuse, including alcohol use disorder * Cancer Category:CNS infections"

New page

== Background ==

=== Microbiology ===

* Most commonly caused by [[Escherichia coli]], [[Klebsiella pneumoniae]], [[Pseudomonas aeruginosa]], and [[Acinetobacter]]
* Also [[Citrobacter]], [[Serratia marcescens]], [[Enterobacter]], and [[Proteus mirabilis]]

=== Risk Factosr ===

* Diabetes mellitus
* Cirrhosis
* End-stage renal disease
* Substance abuse, including alcohol use disorder
* Cancer

[[Category:CNS infections]]