Small cell lung cancer - Revision history

Aidan: /* Background */

2024-01-05T17:27:55Z

Background

← Older revision		Revision as of 17:27, 5 January 2024
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	== Background ==		== Background ==

	* A form of lung cancer that is almost exclusively in smokers, particularly in heavy smokers		* A form of [[lung cancer]] that is almost exclusively in smokers, particularly in heavy smokers

	=== Risk Factors ===		=== Risk Factors ===

Aidan at 17:23, 21 September 2023

2023-09-21T17:23:43Z

← Older revision		Revision as of 17:23, 21 September 2023
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	* Asbestos exposure		* Asbestos exposure
	* Radon exposure		* Radon exposure

			== Clinical Presentation ==

			* May be detected in asymptomatic patients as an incidental finding
			* Potential symptoms include cough, dyspnea, weight loss, and functional decline
			* On imaging, there is most commonly a central, hilar mass with bulky mediastinal lymphadenopathy
			* About 70% have metastatic disease at presentation, including liver, adrenal glands, bone, bone marrow, and brain

	==Staging==		==Staging==

Aidan at 16:03, 21 September 2023

2023-09-21T16:03:57Z

← Older revision		Revision as of 16:03, 21 September 2023
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			== Background ==

			* A form of lung cancer that is almost exclusively in smokers, particularly in heavy smokers

			=== Risk Factors ===

			* '''Tobacco smoking'''
			* Second-hand smoke
			* Asbestos exposure
			* Radon exposure

	==Staging==		==Staging==
	===TMN===		===TMN===

Aidan: /* Staging (TMN) */

2020-07-29T15:10:24Z

Staging (TMN)

← Older revision		Revision as of 15:10, 29 July 2020
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	== Staging ~~(TMN)~~ ==		==Staging==
			===TMN===

	* Stage 1: a single lesion ≤3 cm with no lymphadenopathy		*Stage 1: a single lesion ≤3 cm with no lymphadenopathy
	* Stage 2: ipsilateral lymph nodes and mediastinum		*Stage 2: ipsilateral lymph nodes and mediastinum
	* Stage 3: contralateral lymph nodes and metastases		*Stage 3: contralateral lymph nodes and metastases
	* Stage 4: distant metastases		*Stage 4: distant metastases

	== ~~Staging (~~VALSG) ==		===VALSG===

	* ''Limited stage:'' disease confined to ipsilateral lung, lymph nodes, and mediastinum, which can be contained within one radiotherapy window		*''Limited stage:'' disease confined to ipsilateral lung, lymph nodes, and mediastinum, which can be contained within one radiotherapy window
	* ''Extensive stage:'' metastasis to contralateral lung, contralateral lymph nodes, or distant sites		*''Extensive stage:'' metastasis to contralateral lung, contralateral lymph nodes, or distant sites

	== Management ==		==Management==

	=== Stage 1 ===		===Stage 1===

	* Potentially curative		*Potentially curative
	* Surgical resection		*Surgical resection
	** If lymph nodes negative, adjuvant chemotherapy		**If lymph nodes negative, adjuvant chemotherapy
	** If lymph nodes positive, adjuvant chemoradiotherapy		**If lymph nodes positive, adjuvant chemoradiotherapy
	* The adjuvant chemotherapy is platinum-based		*The adjuvant chemotherapy is platinum-based

	=== Stage 2/Limited Stage ===		===Stage 2/Limited Stage===

	* Not curative		*Not curative
	* Early chemoradiotherapy		*Early chemoradiotherapy

	=== Stage 3 or 4/Extensive Stage ===		===Stage 3 or 4/Extensive Stage===

	* Not curative		*Not curative
	* Chemotherapy extends median survival from 3 months to 8 to 13 months		*Chemotherapy extends median survival from 3 months to 8 to 13 months
	* Prophylactic cranial irradiation		*Prophylactic cranial irradiation

	[[Category:Respirology]]		[[Category:Respirology]]

Maintenance script: Imported from text file

2020-07-04T01:17:56Z

Imported from text file

New page

== Staging (TMN) ==

* Stage 1: a single lesion ≤3 cm with no lymphadenopathy
* Stage 2: ipsilateral lymph nodes and mediastinum
* Stage 3: contralateral lymph nodes and metastases
* Stage 4: distant metastases

== Staging (VALSG) ==

* ''Limited stage:'' disease confined to ipsilateral lung, lymph nodes, and mediastinum, which can be contained within one radiotherapy window
* ''Extensive stage:'' metastasis to contralateral lung, contralateral lymph nodes, or distant sites

== Management ==

=== Stage 1 ===

* Potentially curative
* Surgical resection
** If lymph nodes negative, adjuvant chemotherapy
** If lymph nodes positive, adjuvant chemoradiotherapy
* The adjuvant chemotherapy is platinum-based

=== Stage 2/Limited Stage ===

* Not curative
* Early chemoradiotherapy

=== Stage 3 or 4/Extensive Stage ===

* Not curative
* Chemotherapy extends median survival from 3 months to 8 to 13 months
* Prophylactic cranial irradiation

[[Category:Respirology]]
[[Category:Oncology]]