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	<id>https://idwiki.org/index.php?action=history&amp;feed=atom&amp;title=Secondary_hemolytic-uremic_syndrome</id>
	<title>Secondary hemolytic-uremic syndrome - Revision history</title>
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	<updated>2026-04-28T19:30:47Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://idwiki.org/index.php?title=Secondary_hemolytic-uremic_syndrome&amp;diff=10604&amp;oldid=prev</id>
		<title>Aidan at 16:43, 23 August 2024</title>
		<link rel="alternate" type="text/html" href="https://idwiki.org/index.php?title=Secondary_hemolytic-uremic_syndrome&amp;diff=10604&amp;oldid=prev"/>
		<updated>2024-08-23T16:43:28Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 16:43, 23 August 2024&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 5:&lt;/td&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 5:&lt;/td&gt;
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&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*Associated with autoimmune diseases, transplantation, malignancy, infection, cytotoxic mediation, or pregnancy&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*Associated with autoimmune diseases, transplantation, malignancy, infection, cytotoxic mediation, or pregnancy&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Most common associations are with [[Streptococcus pneumoniae]] and [[influenza]]&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Most common associations are with [[Streptococcus pneumoniae]] and [[influenza]]&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Possibly acute [[Clostridioides difficile]][[&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;SiteRef&lt;/del&gt;::keshtkar-jahromi2012he]][[CiteRef::khurshid2020at]][[CiteRef::alvarado2014he]]&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Possibly acute [[Clostridioides difficile]][[&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;CiteRef&lt;/ins&gt;::keshtkar-jahromi2012he]][[CiteRef::khurshid2020at]][[CiteRef::alvarado2014he]]&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Solid organ transplantation]], mostly in the month or months after transplantation but rarely after a year[[CiteRef::caires2012de]]&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Solid organ transplantation]], mostly in the month or months after transplantation but rarely after a year[[CiteRef::caires2012de]]&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Hematopoietic stem cell transplantation]], up to months to years after transplant&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Hematopoietic stem cell transplantation]], up to months to years after transplant&lt;/div&gt;&lt;/td&gt;
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		<author><name>Aidan</name></author>
	</entry>
	<entry>
		<id>https://idwiki.org/index.php?title=Secondary_hemolytic-uremic_syndrome&amp;diff=10603&amp;oldid=prev</id>
		<title>Aidan at 16:42, 23 August 2024</title>
		<link rel="alternate" type="text/html" href="https://idwiki.org/index.php?title=Secondary_hemolytic-uremic_syndrome&amp;diff=10603&amp;oldid=prev"/>
		<updated>2024-08-23T16:42:07Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 16:42, 23 August 2024&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 5:&lt;/td&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 5:&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*Associated with autoimmune diseases, transplantation, malignancy, infection, cytotoxic mediation, or pregnancy&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*Associated with autoimmune diseases, transplantation, malignancy, infection, cytotoxic mediation, or pregnancy&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Most common associations are with [[Streptococcus pneumoniae]] and [[influenza]]&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Most common associations are with [[Streptococcus pneumoniae]] and [[influenza]]&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-empty diff-side-deleted&quot;&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Possibly acute [[Clostridioides difficile]][[SiteRef::keshtkar-jahromi2012he]][[CiteRef::khurshid2020at]][[CiteRef::alvarado2014he]]&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Possibly acute [[Clostridioides difficile]]&amp;lt;ref&amp;gt;Keshtkar-Jahromi M, Mohebtash M. Hemolytic uremic syndrome and Clostridium difficile colitis. J Community Hosp Intern Med Perspect. 2012 Oct 15;2(3). doi: [https://doi.org/10.3402/jchimp.v2i3.19064 10.3402/jchimp.v2i3.19064]. PMID: [https://pubmed.ncbi.nlm.nih.gov/23882375/ 23882375]; PMCID: [http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3714067/ PMC3714067].&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;Khurshid Q, Mahmoud A, Shahid M, Mohamed A, Shahbaz A. Atypical Hemolytic Uremic Syndrome Associated With Clostridium Difficile Infection. Cureus. 2020 Jul 5;12(7):e9005. doi: [https://doi.org/10.7759%2Fcureus.9005 10.7759/cureus.9005]. PMID: [https://pubmed.ncbi.nlm.nih.gov/32775085 32775085]; PMCID: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402547/ PMC7402547].&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;Alvarado AS, Brodsky SV, Nadasdy T, Singh N. Hemolytic uremic syndrome associated with Clostridium difficile infection. Clin Nephrol. 2014 Apr;81(4):302-6. doi: [https://doi.org/10.5414/cn107691 10.5414/CN107691]. PMID: [https://pubmed.ncbi.nlm.nih.gov/23320969/ 23320969].&amp;lt;/ref&amp;gt;&lt;/div&gt;&lt;/td&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-empty diff-side-added&quot;&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Solid organ transplantation]], mostly in the month or months after transplantation but rarely after a year&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;ref&amp;gt;Caires RA, Marques ID, Repizo LP, Sato VA, Carmo LP, Machado DJ, de Paula FJ, Nahas WC, David-Neto E. De novo thrombotic microangiopathy after kidney transplantation&lt;/del&gt;:&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt; clinical features, treatment, and long-term patient and graft survival. Transplant Proc. 2012 Oct;44(8)&lt;/del&gt;:&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;2388-90. doi: [https://doi.org/10.1016/j.transproceed.2012.07.039 10.1016/j.transproceed.2012.07.039&lt;/del&gt;]&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;. PMID: [https://pubmed.ncbi.nlm.nih.gov/23026601/ 23026601&lt;/del&gt;]&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;.&amp;lt;/ref&amp;gt;&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Solid organ transplantation]], mostly in the month or months after transplantation but rarely after a year&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[CiteRef&lt;/ins&gt;::&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;caires2012de&lt;/ins&gt;]]&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Hematopoietic stem cell transplantation]], up to months to years after transplant&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Hematopoietic stem cell transplantation]], up to months to years after transplant&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-empty diff-side-deleted&quot;&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Systemic lupus erythematosus]][[CiteRef::hughson1992re]]&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Systemic lupus erythematosus]]&amp;lt;ref&amp;gt;Hughson MD, Nadasdy T, McCarty GA, Sholer C, Min KW, Silva F. Renal thrombotic microangiopathy in patients with systemic lupus erythematosus and the antiphospholipid syndrome. Am J Kidney Dis. 1992 Aug;20(2):150-8. doi: [https://doi.org/10.1016/s0272-6386(12)80543-9 10.1016/s0272-6386(12)80543-9]. PMID: [[1496968]].&amp;lt;/ref&amp;gt;&lt;/div&gt;&lt;/td&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-empty diff-side-added&quot;&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Multiple solid organ malignancies (usually metastatic) are associated with [[TMA]], though prostate cancer (non-metastatic) appears to favour an HUS-like pattern&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;ref&amp;gt;Lechner K, Obermeier HL. Cancer-related microangiopathic hemolytic anemia&lt;/del&gt;:&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt; clinical and laboratory features in 168 reported cases. Medicine (Baltimore). 2012 Jul;91(4)&lt;/del&gt;:&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;195-205. doi: [https://doi.org/10.1097/MD.0b013e3182603598 10.1097/MD.0b013e3182603598&lt;/del&gt;]&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;. PMID: [https://pubmed.ncbi.nlm.nih.gov/22732949/ 22732949&lt;/del&gt;]&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;.&amp;lt;/ref&amp;gt;&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Multiple solid organ malignancies (usually metastatic) are associated with [[TMA]], though prostate cancer (non-metastatic) appears to favour an HUS-like pattern&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[CiteRef&lt;/ins&gt;::&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;lechner2012ca&lt;/ins&gt;]]&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-empty diff-side-deleted&quot;&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Normal [[pregnancy]][[CiteRef::egbor2011pr]]&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Normal [[pregnancy]]&amp;lt;ref&amp;gt;Egbor M, Johnson A, Harris F, Makanjoula D, Shehata H. Pregnancy-associated atypical haemolytic uraemic syndrome in the postpartum period: a case report and review of the literature. Obstet Med. 2011 Jun;4(2):83-5. doi: [https://doi.org/10.1258/om.2011.100059 10.1258/om.2011.100059]. Epub 2011 Jun 9. PMID: [https://pubmed.ncbi.nlm.nih.gov/27582861/ 27582861]; PMCID: PMC4989735.&amp;lt;/ref&amp;gt;&lt;/div&gt;&lt;/td&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-empty diff-side-added&quot;&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Drug-induced thrombotic microangiopathy]]&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Drug-induced thrombotic microangiopathy]]&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Category:Thrombotic microangiopathies]]&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[Category:Thrombotic microangiopathies]]&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;

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&lt;/table&gt;</summary>
		<author><name>Aidan</name></author>
	</entry>
	<entry>
		<id>https://idwiki.org/index.php?title=Secondary_hemolytic-uremic_syndrome&amp;diff=9919&amp;oldid=prev</id>
		<title>Aidan: added C diff</title>
		<link rel="alternate" type="text/html" href="https://idwiki.org/index.php?title=Secondary_hemolytic-uremic_syndrome&amp;diff=9919&amp;oldid=prev"/>
		<updated>2023-04-20T14:10:05Z</updated>

		<summary type="html">&lt;p&gt;added C diff&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 14:10, 20 April 2023&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 5:&lt;/td&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 5:&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*Associated with autoimmune diseases, transplantation, malignancy, infection, cytotoxic mediation, or pregnancy&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*Associated with autoimmune diseases, transplantation, malignancy, infection, cytotoxic mediation, or pregnancy&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Most common associations are with [[Streptococcus pneumoniae]] and [[influenza]]&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Most common associations are with [[Streptococcus pneumoniae]] and [[influenza]]&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td colspan=&quot;2&quot; class=&quot;diff-empty diff-side-deleted&quot;&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Possibly acute [[Clostridioides difficile]]&amp;lt;ref&amp;gt;Keshtkar-Jahromi M, Mohebtash M. Hemolytic uremic syndrome and Clostridium difficile colitis. J Community Hosp Intern Med Perspect. 2012 Oct 15;2(3). doi: [https://doi.org/10.3402/jchimp.v2i3.19064 10.3402/jchimp.v2i3.19064]. PMID: [https://pubmed.ncbi.nlm.nih.gov/23882375/ 23882375]; PMCID: [http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3714067/ PMC3714067].&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;Khurshid Q, Mahmoud A, Shahid M, Mohamed A, Shahbaz A. Atypical Hemolytic Uremic Syndrome Associated With Clostridium Difficile Infection. Cureus. 2020 Jul 5;12(7):e9005. doi: [https://doi.org/10.7759%2Fcureus.9005 10.7759/cureus.9005]. PMID: [https://pubmed.ncbi.nlm.nih.gov/32775085 32775085]; PMCID: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402547/ PMC7402547].&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;Alvarado AS, Brodsky SV, Nadasdy T, Singh N. Hemolytic uremic syndrome associated with Clostridium difficile infection. Clin Nephrol. 2014 Apr;81(4):302-6. doi: [https://doi.org/10.5414/cn107691 10.5414/CN107691]. PMID: [https://pubmed.ncbi.nlm.nih.gov/23320969/ 23320969].&amp;lt;/ref&amp;gt;&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Solid organ transplantation]], mostly in the month or months after transplantation but rarely after a year&amp;lt;ref&amp;gt;Caires RA, Marques ID, Repizo LP, Sato VA, Carmo LP, Machado DJ, de Paula FJ, Nahas WC, David-Neto E. De novo thrombotic microangiopathy after kidney transplantation: clinical features, treatment, and long-term patient and graft survival. Transplant Proc. 2012 Oct;44(8):2388-90. doi: [https://doi.org/10.1016/j.transproceed.2012.07.039 10.1016/j.transproceed.2012.07.039]. PMID: [https://pubmed.ncbi.nlm.nih.gov/23026601/ 23026601].&amp;lt;/ref&amp;gt;&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Solid organ transplantation]], mostly in the month or months after transplantation but rarely after a year&amp;lt;ref&amp;gt;Caires RA, Marques ID, Repizo LP, Sato VA, Carmo LP, Machado DJ, de Paula FJ, Nahas WC, David-Neto E. De novo thrombotic microangiopathy after kidney transplantation: clinical features, treatment, and long-term patient and graft survival. Transplant Proc. 2012 Oct;44(8):2388-90. doi: [https://doi.org/10.1016/j.transproceed.2012.07.039 10.1016/j.transproceed.2012.07.039]. PMID: [https://pubmed.ncbi.nlm.nih.gov/23026601/ 23026601].&amp;lt;/ref&amp;gt;&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;
&lt;tr&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Hematopoietic stem cell transplantation]], up to months to years after transplant&lt;/div&gt;&lt;/td&gt;
  &lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;
  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**[[Hematopoietic stem cell transplantation]], up to months to years after transplant&lt;/div&gt;&lt;/td&gt;
&lt;/tr&gt;

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&lt;/table&gt;</summary>
		<author><name>Aidan</name></author>
	</entry>
	<entry>
		<id>https://idwiki.org/index.php?title=Secondary_hemolytic-uremic_syndrome&amp;diff=9917&amp;oldid=prev</id>
		<title>Aidan: Created page with &quot; ==Background== *One of the thrombotic microangiopathies *Different pathophysiology and treatment from typical hemolytic-uremic syndrome (after STEC diarrhea) and atypical hemolytic-uremic syndrome (though often grouped with aHUS) *Associated with autoimmune diseases, transplantation, malignancy, infection, cytotoxic mediation, or pregnancy **Most common associations are with Streptococcus pneumoniae an...&quot;</title>
		<link rel="alternate" type="text/html" href="https://idwiki.org/index.php?title=Secondary_hemolytic-uremic_syndrome&amp;diff=9917&amp;oldid=prev"/>
		<updated>2023-04-20T13:53:26Z</updated>

		<summary type="html">&lt;p&gt;Created page with &amp;quot; ==Background== *One of the &lt;a href=&quot;/Thrombotic_microangiopathy&quot; title=&quot;Thrombotic microangiopathy&quot;&gt;thrombotic microangiopathies&lt;/a&gt; *Different pathophysiology and treatment from &lt;a href=&quot;/Hemolytic-uremic_syndrome&quot; title=&quot;Hemolytic-uremic syndrome&quot;&gt;typical hemolytic-uremic syndrome&lt;/a&gt; (after STEC diarrhea) and &lt;a href=&quot;/Atypical_hemolytic-uremic_syndrome&quot; title=&quot;Atypical hemolytic-uremic syndrome&quot;&gt;atypical hemolytic-uremic syndrome&lt;/a&gt; (though often grouped with aHUS) *Associated with autoimmune diseases, transplantation, malignancy, infection, cytotoxic mediation, or pregnancy **Most common associations are with &lt;a href=&quot;/Streptococcus_pneumoniae&quot; title=&quot;Streptococcus pneumoniae&quot;&gt;&lt;i&gt;Streptococcus pneumoniae&lt;/i&gt;&lt;/a&gt; an...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&lt;br /&gt;
==Background==&lt;br /&gt;
*One of the [[thrombotic microangiopathy|thrombotic microangiopathies]]&lt;br /&gt;
*Different pathophysiology and treatment from [[hemolytic-uremic syndrome|typical hemolytic-uremic syndrome]] (after STEC diarrhea) and [[atypical hemolytic-uremic syndrome]] (though often grouped with aHUS)&lt;br /&gt;
*Associated with autoimmune diseases, transplantation, malignancy, infection, cytotoxic mediation, or pregnancy&lt;br /&gt;
**Most common associations are with [[Streptococcus pneumoniae]] and [[influenza]]&lt;br /&gt;
**[[Solid organ transplantation]], mostly in the month or months after transplantation but rarely after a year&amp;lt;ref&amp;gt;Caires RA, Marques ID, Repizo LP, Sato VA, Carmo LP, Machado DJ, de Paula FJ, Nahas WC, David-Neto E. De novo thrombotic microangiopathy after kidney transplantation: clinical features, treatment, and long-term patient and graft survival. Transplant Proc. 2012 Oct;44(8):2388-90. doi: [https://doi.org/10.1016/j.transproceed.2012.07.039 10.1016/j.transproceed.2012.07.039]. PMID: [https://pubmed.ncbi.nlm.nih.gov/23026601/ 23026601].&amp;lt;/ref&amp;gt;&lt;br /&gt;
**[[Hematopoietic stem cell transplantation]], up to months to years after transplant&lt;br /&gt;
**[[Systemic lupus erythematosus]]&amp;lt;ref&amp;gt;Hughson MD, Nadasdy T, McCarty GA, Sholer C, Min KW, Silva F. Renal thrombotic microangiopathy in patients with systemic lupus erythematosus and the antiphospholipid syndrome. Am J Kidney Dis. 1992 Aug;20(2):150-8. doi: [https://doi.org/10.1016/s0272-6386(12)80543-9 10.1016/s0272-6386(12)80543-9]. PMID: [[1496968]].&amp;lt;/ref&amp;gt;&lt;br /&gt;
**Multiple solid organ malignancies (usually metastatic) are associated with [[TMA]], though prostate cancer (non-metastatic) appears to favour an HUS-like pattern&amp;lt;ref&amp;gt;Lechner K, Obermeier HL. Cancer-related microangiopathic hemolytic anemia: clinical and laboratory features in 168 reported cases. Medicine (Baltimore). 2012 Jul;91(4):195-205. doi: [https://doi.org/10.1097/MD.0b013e3182603598 10.1097/MD.0b013e3182603598]. PMID: [https://pubmed.ncbi.nlm.nih.gov/22732949/ 22732949].&amp;lt;/ref&amp;gt;&lt;br /&gt;
**Normal [[pregnancy]]&amp;lt;ref&amp;gt;Egbor M, Johnson A, Harris F, Makanjoula D, Shehata H. Pregnancy-associated atypical haemolytic uraemic syndrome in the postpartum period: a case report and review of the literature. Obstet Med. 2011 Jun;4(2):83-5. doi: [https://doi.org/10.1258/om.2011.100059 10.1258/om.2011.100059]. Epub 2011 Jun 9. PMID: [https://pubmed.ncbi.nlm.nih.gov/27582861/ 27582861]; PMCID: PMC4989735.&amp;lt;/ref&amp;gt;&lt;br /&gt;
**[[Drug-induced thrombotic microangiopathy]]&lt;br /&gt;
[[Category:Thrombotic microangiopathies]]&lt;/div&gt;</summary>
		<author><name>Aidan</name></author>
	</entry>
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