https://idwiki.org/index.php?action=history&feed=atom&title=Scleroderma_renal_crisis 2026-05-13T00:53:01Z Revision history for this page on the wiki MediaWiki 1.43.8 https://idwiki.org/index.php?title=Scleroderma_renal_crisis&diff=5397&oldid=prev 2020-08-02T10:58:30Z

<p>Text replacement - &quot;== Clinical Presentation&quot; to &quot;== Clinical Manifestations&quot;</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 10:58, 2 August 2020</td> </tr><tr> <td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== Clinical <del style="font-weight: bold; text-decoration: none;">Presentation</del> ==</div></td> <td class="diff-marker" data-marker="+"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>== Clinical <ins style="font-weight: bold; text-decoration: none;">Manifestations</ins> ==</div></td> </tr> <tr> <td class="diff-marker"></td> <td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br /></td> <td class="diff-marker"></td> <td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br /></td> </tr> <tr> <td class="diff-marker"></td> <td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Acute onset renal failure without another cause</div></td> <td class="diff-marker"></td> <td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Acute onset renal failure without another cause</div></td> </tr> </table>

Aidan https://idwiki.org/index.php?title=Scleroderma_renal_crisis&diff=4455&oldid=prev 2020-07-04T01:17:55Z

<p>Imported from text file</p> <p><b>New page</b></p><div>== Clinical Presentation ==<br /> <br /> * Acute onset renal failure without another cause<br /> ** Bland urine sediment, though can have proteinuria and hematoria<br /> * Acute onset moderate tosevere hypertension, often with hypertensive emergency<br /> ** Papilledema<br /> ** Hypertensive retinopathy<br /> ** Hypertensive encephalopathy<br /> * Additional findings<br /> ** Bicytopenia with MAHA and thrombocytopenia<br /> ** Flash pulmonary edema<br /> ** New-onset proteinuria or hematuria without other cause<br /> <br /> == Management ==<br /> <br /> * Blood pressure control, primarily with &#039;&#039;&#039;ACE inhibitors&#039;&#039;&#039;, is the primary treatment<br /> ** First-line: captopril has the most evidence<br /> *** Initial dose 6.25 to 12.5 mg, increase by 12.5 to 25 mg every 4 to 8 hours to achieve target<br /> ** Alternatives: enalapril or ramipril<br /> ** Target return to baseline BP within 72 hours, with about 20 mmHg reduction daily<br /> * For CNS disease, can add &#039;&#039;&#039;nitroprusside&#039;&#039;&#039;<br /> * Monitor creatinine<br /> <br /> == Prevention ==<br /> <br /> * No clear role for ACE inhibitors for primary prevention<br /> * ACE inhibitors are continued indefinitely for secondary prevention<br /> * Avoid beta blockers, which can worsen Raynaud phenomenon<br /> * Avoid glucocorticoids if possible, as they can precipitate crises<br /> <br /> == Prognosis ==<br /> <br /> * Untreated, SRC progresses to ESRD within month<br /> * Treated, 20 to 50% still end up on dialysis<br /> <br /> [[Category:Rheumatology]]<br /> [[Category:Nephrology]]</div>

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