Sarcocystis - Revision history

Aidan: Aidan moved page Sarcocystis species to Sarcocystis over a redirect without leaving a redirect

2022-01-25T16:53:35Z

Aidan moved page Sarcocystis species to Sarcocystis over a redirect without leaving a redirect

← Older revision		Revision as of 16:53, 25 January 2022
(No difference)

Aidan at 16:53, 25 January 2022

2022-01-25T16:53:28Z

← Older revision		Revision as of 16:53, 25 January 2022
Line 40:		Line 40:
	* No known effective antiparasitic, although [[albendazole]] has been tried at least once		* No known effective antiparasitic, although [[albendazole]] has been tried at least once

	{{DISPLAYTITLE:''Sarcocystis''		{{DISPLAYTITLE:''Sarcocystis''}}
	[[Category:Protozoa]]		[[Category:Protozoa]]

Aidan: Text replacement - " species}}" to ""

2022-01-25T16:40:50Z

Text replacement - " species}}" to ""

← Older revision		Revision as of 16:40, 25 January 2022
Line 40:		Line 40:
	* No known effective antiparasitic, although [[albendazole]] has been tried at least once		* No known effective antiparasitic, although [[albendazole]] has been tried at least once

	{{DISPLAYTITLE:''Sarcocystis'' ~~species}}~~		{{DISPLAYTITLE:''Sarcocystis''
	[[Category:Protozoa]]		[[Category:Protozoa]]

Aidan: /* Clinical Manifestations */

2020-08-05T13:49:48Z

Clinical Manifestations

← Older revision		Revision as of 13:49, 5 August 2020
Line 25:		Line 25:
	* Mostly asymptomatic		* Mostly asymptomatic
	* If symptomatic, may cause nausea, abdominal discomfort, diarrhea, and fever		* If symptomatic, may cause nausea, abdominal discomfort, diarrhea, and fever
	* Incubation period, if diarrhea is a symptom, of ~~two~~ days		* Incubation period, if diarrhea is a symptom, of [[Usual incubation period::2 days]]
	* Self-limited illness		* Self-limited illness

Aidan: Text replacement - "Clinical Presentation" to "Clinical Manifestations"

2020-07-19T05:53:51Z

Text replacement - "Clinical Presentation" to "Clinical Manifestations"

← Older revision		Revision as of 05:53, 19 July 2020
Line 21:		Line 21:
	** It takes about two months to become infections		** It takes about two months to become infections

	== Clinical ~~Presentation~~ ==		== Clinical Manifestations ==
	=== Human intestinal sarcocystosis ===		=== Human intestinal sarcocystosis ===
	* Mostly asymptomatic		* Mostly asymptomatic

Aidan: /* Human muscular sarcocystosis */ linked

2019-12-03T00:09:12Z

Human muscular sarcocystosis: linked

← Older revision		Revision as of 00:09, 3 December 2019
Line 29:		Line 29:

	=== Human muscular sarcocystosis ===		=== Human muscular sarcocystosis ===
	* Mostly asymptomatic, but can develop a fulminant '''eosinophilic myositis'''		* Mostly asymptomatic, but can develop a fulminant '''[[Causes::eosinophilic myositis]]'''
	* May develop fever, myalgias, eosinophilia, and elevated CK		* May develop fever, myalgias, eosinophilia, and elevated CK

Aidan: /* Clinical Presentation */

2019-12-02T23:45:34Z

Clinical Presentation

← Older revision		Revision as of 23:45, 2 December 2019
Line 24:		Line 24:
	=== Human intestinal sarcocystosis ===		=== Human intestinal sarcocystosis ===
	* Mostly asymptomatic		* Mostly asymptomatic
	* If symptomatic, may cause nausea, abdominal discomfort, and ~~diarrhea~~		* If symptomatic, may cause nausea, abdominal discomfort, diarrhea, and fever
	* Incubation period, if diarrhea is a symptom, of two days		* Incubation period, if diarrhea is a symptom, of two days
	* Self-limited illness		* Self-limited illness

	=== Human muscular sarcocystosis ===		=== Human muscular sarcocystosis ===
	* Mostly asymptomatic		* Mostly asymptomatic, but can develop a fulminant '''eosinophilic myositis'''
	* May develop fever, myalgias, and ~~eosinophilia~~		* May develop fever, myalgias, eosinophilia, and elevated CK

	== Diagnosis ==		== Diagnosis ==

Aidan: /* Diagnosis */

2019-10-10T14:04:42Z

Diagnosis

← Older revision		Revision as of 14:04, 10 October 2019
Line 33:		Line 33:

	== Diagnosis ==		== Diagnosis ==
	* Stool ~~O&P~~ for intestinal disease		* Stool microscopy for intestinal disease
	* Muscle biopsy for muscle disease		* Muscle biopsy for muscle disease

Aidan: /* Epidemiology */

2019-10-10T14:04:13Z

Epidemiology

← Older revision		Revision as of 14:04, 10 October 2019
Line 7:		Line 7:

	=== Epidemiology ===		=== Epidemiology ===
	* Zoonosis of ~~mice~~ and ~~other~~ ~~animals~~, with a two-host cycle		* Zoonosis of primarily of cattle (''S. hominis'') and pork (''S. suihominis''), with a two-host cycle
	* Worldwide, but most cases are in tropics or subtropics of Southeast Asia (especially Malaysia)		* Worldwide, but most cases are in tropics or subtropics of Southeast Asia (especially Malaysia)

Aidan: added clin pres through to management

2019-10-10T00:47:25Z

added clin pres through to management

← Older revision		Revision as of 00:47, 10 October 2019
Line 1:		Line 1:
	* Protozoan infection of ~~muscle~~ ~~acquired~~ ~~from~~ ~~snake~~ ~~feces~~		* Protozoan infection that can cause gastrointestinal or muscle disease

			== Background ==
			=== Microbiology ===
			* Species that cause human intestinal sarcocystosis include ''[[Sarcocystis hominis]]'' and ''[[Sarcocystis suihominis]]''
			* Other species may be involved in causing human muscular sarcocystosis (as incidental hosts)

			=== Epidemiology ===
			* Zoonosis of mice and other animals, with a two-host cycle
			* Worldwide, but most cases are in tropics or subtropics of Southeast Asia (especially Malaysia)

			=== Life Cycle ===
			* Tissue '''sarcocyst''' is eaten by the definitive host
			* Sarcocyst releases motile '''bradyzoites''' which penetrate into the lamina propria
			* Bradyzoites mature into male and female forms, followed by sexual reproduction creating '''oocysts'''
			* Mature oocysts (containing two '''sporocysts''') are shed
			* Sporocysts are eaten by the other host
			* Sporocysts release '''sporozoites''', which penetrate the intestinal all and enter the vascular endothelium
			* Asexual reproduction creates '''merozoites''', which spread hematogenously to muscle
			* In muscle, the merozoites develops into a sarcocyst, which contains two bradyzoites
			** It takes about two months to become infections

			== Clinical Presentation ==
			=== Human intestinal sarcocystosis ===
			* Mostly asymptomatic
			* If symptomatic, may cause nausea, abdominal discomfort, and diarrhea
			* Incubation period, if diarrhea is a symptom, of two days
			* Self-limited illness

			=== Human muscular sarcocystosis ===
			* Mostly asymptomatic
			* May develop fever, myalgias, and eosinophilia

			== Diagnosis ==
			* Stool O&P for intestinal disease
			* Muscle biopsy for muscle disease

			== Management ==
			* Supportive
			* No known effective antiparasitic, although [[albendazole]] has been tried at least once

	{{DISPLAYTITLE:''Sarcocystis'' species}}		{{DISPLAYTITLE:''Sarcocystis'' species}}