Rickettsia conorii - Revision history

Aidan: /* Clinical Manifestations */

2020-08-05T13:49:57Z

Clinical Manifestations

← Older revision		Revision as of 13:49, 5 August 2020
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	== Clinical Manifestations ==		== Clinical Manifestations ==
	* Incubation period of 7 days		* Incubation period of [[Usual incubation period::7 days]]
	* Initial symptoms include fever, myalgias, and headache		* Initial symptoms include fever, myalgias, and headache
	* Often has an eschar at the site of tick bit inoculation ('''"tache noir"'''), but not always		* Often has an eschar at the site of tick bit inoculation ('''"tache noir"'''), but not always

Aidan: Text replacement - "Clinical Presentation" to "Clinical Manifestations"

2020-07-14T23:07:09Z

Text replacement - "Clinical Presentation" to "Clinical Manifestations"

← Older revision		Revision as of 23:07, 14 July 2020
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	* More cases occur during the warm months (July through September in the Mediterranean)		* More cases occur during the warm months (July through September in the Mediterranean)

	== Clinical ~~Presentation~~ ==		== Clinical Manifestations ==
	* Incubation period of 7 days		* Incubation period of 7 days
	* Initial symptoms include fever, myalgias, and headache		* Initial symptoms include fever, myalgias, and headache

Aidan: /* Management */

2020-03-14T23:43:18Z

Management

← Older revision		Revision as of 23:43, 14 March 2020
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	== Management ==		== Management ==
	* First-line: [[Is treated by::doxycycline]] 100 mg po bid for 7 days		* First-line: [[Is treated by::doxycycline]] 100 mg po bid for 7 days (at least 5-7 days and resolution of symptoms for 3 days)
	** May be able to shorten to a single day of two doses of 200 mg each		** May be able to shorten to a single day of two doses of 200 mg each in one small study
	** Could use [[Is treated by::minocycline]]		** Could use [[Is treated by::minocycline]]
	* [[Is treated by::Ciprofloxacin]] ~~may be considered, but may be~~ associated with a more severe course		* [[Is treated by::Ciprofloxacin]] is associated with a more severe course and should be avoided
	* [[Is treated by::Azithromycin]] or [[Is treated by::clarithromycin]] may be considered in pregnant women or children		* [[Is treated by::Azithromycin]] or [[Is treated by::clarithromycin]] may be considered in pregnant women or children

Aidan: /* Management */

2020-03-14T03:08:50Z

Management

← Older revision		Revision as of 03:08, 14 March 2020
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	== Management ==		== Management ==
	* First-line: [[Is treated by::doxycycline]] 100 mg po bid for 7 days		* First-line: [[Is treated by::doxycycline]] 100 mg po bid for 7 days
	** May be able to shorten to a single day ~~with~~ two doses		** May be able to shorten to a single day of two doses of 200 mg each
	** Could use [[Is treated by::minocycline]])		** Could use [[Is treated by::minocycline]]
	* [[Is treated by::Ciprofloxacin]] may be considered, but may be associated with a more severe course		* [[Is treated by::Ciprofloxacin]] may be considered, but may be associated with a more severe course
	* [[Is treated by::Azithromycin]] or [[Is treated by::clarithromycin]] may be considered in pregnant women or children		* [[Is treated by::Azithromycin]] or [[Is treated by::clarithromycin]] may be considered in pregnant women or children

Aidan at 01:35, 14 March 2020

2020-03-14T01:35:14Z

← Older revision		Revision as of 01:35, 14 March 2020
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	* A tickborne rickettsial species that causes boutonneuse fever		* A tickborne rickettsial species that causes '''boutonneuse fever''', the most severe form of rickettsial spotted fever next to [[Rocky Mountain spotted fever]]
		⚫	* Also known as Marseilles fever, Mediterranean spotted fever, Kenya tick typhus, Israeli tick typhus, Astrakhan spotted fever, and Indian tick typhus

	== ~~Epidemiology~~ ==		== Background ==
			=== Microbiology ===
			* Species of ''[[Rickettsia]]'' within the spotted fever group

			=== Life Cycle ===
⚫	* Transmitted by ''Rhipicephalus sanguineus'' ticks
			* Maintained transovarially within the tick species

			=== Epidemiology ===
		⚫	* Transmitted by ''[[Rhipicephalus sanguineus]]'' ticks
	* Founds in India, Pakistan, Israel, Russia, Georgia, Bulgaria, Turkey, Ukraine, Ethiopia, Kenya, South Africa, Morocco, and southern Europe		* Founds in India, Pakistan, Israel, Russia, Georgia, Bulgaria, Turkey, Ukraine, Ethiopia, Kenya, South Africa, Morocco, and southern Europe
			* More cases occur during the warm months (July through September in the Mediterranean)

	== Clinical Presentation ==		== Clinical Presentation ==
			* Incubation period of 7 days

			* Initial symptoms include fever, myalgias, and headache
⚫	* Also known as Marseilles fever, Mediterranean spotted fever, Kenya tick typhus, Israeli tick typhus, Astrakhan spotted fever, and Indian tick typhus
	* Often has an eschar at the site of tick bit ~~innoculation~~ (~~"~~tache noir~~"~~), but not always		* Often has an eschar at the site of tick bit inoculation ('''"tache noir"'''), but not always
	* Petechial rash, GI symptoms, obtundation, tachypnea, hepatomegaly, leukocytosis, coagulopathy, AKI, bilirubin elevation, AST elevation, and CK elevation		* Petechial rash, GI symptoms, obtundation, tachypnea, hepatomegaly, leukocytosis, coagulopathy, AKI, bilirubin elevation, AST elevation, and CK elevation
	* Procoagulant, and 10% develop DVT		* Procoagulant, and 10% develop DVT
	* Can present as acute pancreatitis		* Can present as acute pancreatitis
	* Can be quite severe with higher mortality than others in the spotted fever group		* Can be quite severe with higher mortality than others in the spotted fever group

			== Management ==
			* First-line: [[Is treated by::doxycycline]] 100 mg po bid for 7 days
			** May be able to shorten to a single day with two doses
			** Could use [[Is treated by::minocycline]])
			* [[Is treated by::Ciprofloxacin]] may be considered, but may be associated with a more severe course
			* [[Is treated by::Azithromycin]] or [[Is treated by::clarithromycin]] may be considered in pregnant women or children

	{{DISPLAYTITLE:''Rickettsia conorii''}}		{{DISPLAYTITLE:''Rickettsia conorii''}}

Aidan at 20:14, 15 August 2019

2019-08-15T20:14:21Z

← Older revision		Revision as of 20:14, 15 August 2019
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	* A tickborne rickettsial species that causes boutonneuse fever		* A tickborne rickettsial species that causes boutonneuse fever

	= Epidemiology =		== Epidemiology ==

	* Transmitted by ''Rhipicephalus sanguineus'' ticks		* Transmitted by ''Rhipicephalus sanguineus'' ticks
	* Founds in India, Pakistan, Israel, Russia, Georgia, Bulgaria, Turkey, Ukraine, Ethiopia, Kenya, South Africa, Morocco, and southern Europe		* Founds in India, Pakistan, Israel, Russia, Georgia, Bulgaria, Turkey, Ukraine, Ethiopia, Kenya, South Africa, Morocco, and southern Europe

	= Clinical Presentation =		== Clinical Presentation ==

	* Also known as Marseilles fever, Mediterranean spotted fever, Kenya tick typhus, Israeli tick typhus, Astrakhan spotted fever, and Indian tick typhus		* Also known as Marseilles fever, Mediterranean spotted fever, Kenya tick typhus, Israeli tick typhus, Astrakhan spotted fever, and Indian tick typhus

Aidan at 00:29, 15 August 2019

2019-08-15T00:29:23Z

← Older revision		Revision as of 00:29, 15 August 2019
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		⚫	* A tickborne rickettsial species that causes boutonneuse fever
	= Boutonneuse fever (''R. conorii'') =

		⚫	= Epidemiology =
⚫	* ~~''Rickettsia conorii'' is a~~ tickborne rickettsial species that causes boutonneuse fever

⚫	== Epidemiology ==

	* Transmitted by ''Rhipicephalus sanguineus'' ticks		* Transmitted by ''Rhipicephalus sanguineus'' ticks
	* Founds in India, Pakistan, Israel, Russia, Georgia, Bulgaria, Turkey, Ukraine, Ethiopia, Kenya, South Africa, Morocco, and southern Europe		* Founds in India, Pakistan, Israel, Russia, Georgia, Bulgaria, Turkey, Ukraine, Ethiopia, Kenya, South Africa, Morocco, and southern Europe

	== Clinical Presentation ==		= Clinical Presentation =

	* Also known as Marseilles fever, Mediterranean spotted fever, Kenya tick typhus, Israeli tick typhus, Astrakhan spotted fever, and Indian tick typhus		* Also known as Marseilles fever, Mediterranean spotted fever, Kenya tick typhus, Israeli tick typhus, Astrakhan spotted fever, and Indian tick typhus
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	* Can present as acute pancreatitis		* Can present as acute pancreatitis
	* Can be quite severe with higher mortality than others in the spotted fever group		* Can be quite severe with higher mortality than others in the spotted fever group

			{{DISPLAYTITLE:''Rickettsia conorii''}}
			[[Category:Rickettsioses]]

Aidan: Aidan moved page Boutonneuse fever to Rickettsia conorii

2019-08-15T00:28:50Z

Aidan moved page Boutonneuse fever to Rickettsia conorii

← Older revision		Revision as of 00:28, 15 August 2019
(No difference)

Aidan: Aidan moved page Boutonneuse fever (R. conorii) to Boutonneuse fever without leaving a redirect

2019-08-15T00:28:38Z

Aidan moved page Boutonneuse fever (R. conorii) to Boutonneuse fever without leaving a redirect

← Older revision		Revision as of 00:28, 15 August 2019
(No difference)

Maintenance script: Imported from text file

2019-08-11T18:05:49Z

Imported from text file

New page

= Boutonneuse fever (''R. conorii'') =

* ''Rickettsia conorii'' is a tickborne rickettsial species that causes boutonneuse fever

== Epidemiology ==

* Transmitted by ''Rhipicephalus sanguineus'' ticks
* Founds in India, Pakistan, Israel, Russia, Georgia, Bulgaria, Turkey, Ukraine, Ethiopia, Kenya, South Africa, Morocco, and southern Europe

== Clinical Presentation ==

* Also known as Marseilles fever, Mediterranean spotted fever, Kenya tick typhus, Israeli tick typhus, Astrakhan spotted fever, and Indian tick typhus
* Often has an eschar at the site of tick bit innoculation ("tache noir"), but not always
* Petechial rash, GI symptoms, obtundation, tachypnea, hepatomegaly, leukocytosis, coagulopathy, AKI, bilirubin elevation, AST elevation, and CK elevation
* Procoagulant, and 10% develop DVT
* Can present as acute pancreatitis
* Can be quite severe with higher mortality than others in the spotted fever group