Reactive arthritis - Revision history

Aidan at 16:33, 5 February 2024

2024-02-05T16:33:30Z

← Older revision		Revision as of 16:33, 5 February 2024
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	== Definition ==		== Definition ==

	* A syndrome cause by specific infections in a genetically susceptible host that is characterized by conjunctivitis, urethritis, and seronegative arthritis		* A syndrome cause by specific infections in a genetically susceptible host that is characterized by [[conjunctivitis]], [[urethritis]], and [[seronegative arthritis]]

	== Associated Infections ==		== Associated Infections ==

	* Enteric infections		* Enteric infections
	** ''Shigella~~'' spp.~~		** [[Shigella]]
	** ''Salmonella~~'' spp.~~		** [[Salmonella]]
	** ''Yersinia enterocolitica'' and ~~''Y.~~ pseudotuberculosis''		** [[Yersinia enterocolitica]] and [[Yersinia pseudotuberculosis]]
	** ''Campylobacter jejuni''		** [[Campylobacter jejuni]]
	* Genitourinary infections		* Genitourinary infections
	** Chlamydia trachomatis		** [[Chlamydia trachomatis]]

	== Clinical Manifestations ==		== Clinical Manifestations ==
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	* CBC may show mild anemia		* CBC may show mild anemia
	* Synovial fluid non-specific inflammation		* Synovial fluid non-specific inflammation
	* X-rays ~~can~~ show ~~justaarticular~~ osteoporosis		* X-rays may show articular osteoporosis
	** Later findings include marginal erosions, loss of joint space, periostitis, reactive born formation, and plantar spurs		** Later findings include marginal erosions, loss of joint space, periostitis, reactive born formation, and plantar spurs

Aidan: Text replacement - "Clinical Presentation" to "Clinical Manifestations"

2020-07-14T22:56:15Z

Text replacement - "Clinical Presentation" to "Clinical Manifestations"

← Older revision		Revision as of 22:56, 14 July 2020
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	** Chlamydia trachomatis		** Chlamydia trachomatis

	== Clinical ~~Presentation~~ ==		== Clinical Manifestations ==

	* Classic triad of arthritis, urethritis, and conjunctivitis only seen in about a third of patients		* Classic triad of arthritis, urethritis, and conjunctivitis only seen in about a third of patients

Maintenance script: Imported from text file

2020-07-04T01:17:53Z

Imported from text file

New page

== Definition ==

* A syndrome cause by specific infections in a genetically susceptible host that is characterized by conjunctivitis, urethritis, and seronegative arthritis

== Associated Infections ==

* Enteric infections
** ''Shigella'' spp.
** ''Salmonella'' spp.
** ''Yersinia enterocolitica'' and ''Y. pseudotuberculosis''
** ''Campylobacter jejuni''
* Genitourinary infections
** Chlamydia trachomatis

== Clinical Presentation ==

* Classic triad of arthritis, urethritis, and conjunctivitis only seen in about a third of patients
* Onset 1-4 weeks after infection
* May present with constitutional symptoms (fever, malaise, weight loss)
* Arthritis is usually peripheral and axial, symmetric and additive evolving over 1-2 weeks
* Can have dactylitis, enthesistis, tendinitis, and fasciitis
* Oral ulcers are common but often asymptomatic
* Keratoderma blennorhagica, a palmoplantar pustular disease
* Circinate balanitis, painless erosions from ruptured vesicles on the glans

== Investigations ==

* ESR/CRP and acute-phase reactants
* CBC may show mild anemia
* Synovial fluid non-specific inflammation
* X-rays can show justaarticular osteoporosis
** Later findings include marginal erosions, loss of joint space, periostitis, reactive born formation, and plantar spurs

== Management ==

* NSAIDs for symptom relief, though often not helpful
** Indomethacin 75-150mg/d in divided doses

== Prognosis ==

* Symptoms typically resolve over 3-5 months
* Can be chronic (about 15%)

[[Category:Rheumatology]]