Aidan at 18:43, 13 February 2021

2021-02-13T18:43:25Z

← Older revision		Revision as of 18:43, 13 February 2021
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	== Background ==		==Background==

	* On the spectrum of [[necrotizing herpetic retinopathy]], with [[acute retinal necrosis]] on the other end of the spectrum		*On the spectrum of [[necrotizing herpetic retinopathy]], with [[acute retinal necrosis]] on the other end of the spectrum

	=== Microbiology ===		===Microbiology===

	* Overwhelmingly caused by [[varicella-zoster virus]], followed by [[herpes simplex virus]] and rarely by [[cytomegalovirus]]		*Overwhelmingly caused by [[varicella-zoster virus]], followed by [[herpes simplex virus]] and rarely by [[cytomegalovirus]]

	=== Epidemiology ===		===Epidemiology===

	* Most closely associated with advanced HIV (typically with CD4 counts less than 50-100)		*Most closely associated with advanced HIV (typically with CD4 counts less than 50-100)

	== Clinical Manifestions ==		==Clinical Manifestions==

	* Rapidly progressing necrosis of the outer retina, in an immunocompromised patient		*Rapidly progressing necrosis of the outer retina, in an immunocompromised patient
	* 22% have past medical history of cutaneous zoster, half of which had it in a V1 distribution		*22% have past medical history of cutaneous zoster, half of which had it in a V1 distribution
	* May have concurrent cutaneous or central nervous system involvement		*May have concurrent cutaneous or central nervous system involvement
	* May appear similar to [[central retinal arterial occlusion]]		*May appear similar to [[central retinal arterial occlusion]]

			=== Prognosis ===

			* Poor, which most patients becoming blind despite treatment
			* Vision is better if they get intravitreal injections

			== Management ==

			* Consult Ophthalmology
			* [[Ganciclovir]] may be more effective than [[acyclovir]]
			* Should get concomitant intravitreal [[ganciclovir]] or [[foscarnet]]

	[[Category:Herpesviridae]]		[[Category:Herpesviridae]]

Aidan: Created page with "== Background == * On the spectrum of necrotizing herpetic retinopathy, with acute retinal necrosis on the other end of the spectrum === Microbiology === * Overwhel..."

2021-02-13T18:40:54Z

Created page with "== Background == * On the spectrum of necrotizing herpetic retinopathy, with acute retinal necrosis on the other end of the spectrum === Microbiology === * Overwhel..."

New page

== Background ==

* On the spectrum of [[necrotizing herpetic retinopathy]], with [[acute retinal necrosis]] on the other end of the spectrum

=== Microbiology ===

* Overwhelmingly caused by [[varicella-zoster virus]], followed by [[herpes simplex virus]] and rarely by [[cytomegalovirus]]

=== Epidemiology ===

* Most closely associated with advanced HIV (typically with CD4 counts less than 50-100)

== Clinical Manifestions ==

* Rapidly progressing necrosis of the outer retina, in an immunocompromised patient
* 22% have past medical history of cutaneous zoster, half of which had it in a V1 distribution
* May have concurrent cutaneous or central nervous system involvement
* May appear similar to [[central retinal arterial occlusion]]

[[Category:Herpesviridae]]
[[Category:Ocular infections]]

Progressive outer retinal necrosis - Revision history

Aidan at 18:43, 13 February 2021

Aidan: Created page with "== Background == * On the spectrum of necrotizing herpetic retinopathy, with acute retinal necrosis on the other end of the spectrum === Microbiology === * Overwhel..."