Posaconazole - Revision history

Aidan at 15:00, 22 October 2024

2024-10-22T15:00:34Z

← Older revision		Revision as of 15:00, 22 October 2024
Line 104:		Line 104:
	*For prophylaxis, target trough >0.7 mg/L, or random level 0.35 mg/L 48 h after starting therapy		*For prophylaxis, target trough >0.7 mg/L, or random level 0.35 mg/L 48 h after starting therapy
	*For treatment, target trough >1 mg/L		*For treatment, target trough >1 mg/L
			*In Ontario, it may be available through [https://www.chusj.org/labotest/accueil CHU Saine-Justine] in Quebec ([https://chusj.omni-assistant.net/labo/AnalysisRegistry/AnalysisView.aspx?PK_Analysis=446 link to LTIG entry])

	== Safety ==		== Safety ==

Aidan at 13:39, 22 October 2024

2024-10-22T13:39:28Z

@@ Line 1: / Line 1: @@
 ===Clinical Breakpoints===
@@ Line 95: / Line 97: @@
 |>0.25
 |}
 == Safety ==

Aidan: added EUCAST ECOFFs and breakpoints

2024-10-22T13:05:42Z

added EUCAST ECOFFs and breakpoints

@@ Line 10: / Line 10: @@
 ! rowspan="2" |ECV (μg/mL)
 ! colspan="4" |Breakpoints (μg/mL)
 |-
 !S
 !I
 !SDD
 !R
 |-
@@ Line 24: / Line 19: @@
 |0.06
 |≤0.06
 |≥0.12
 |-
 |[[Candida dubliniensis]]
+|
+|
@@ Line 45: / Line 29: @@
 |[[Candida glabrata]]
 |2
+|
+|
@@ Line 56: / Line 34: @@
 |[[Candida guilliermondii]]
 |0.5
+|
+|
@@ Line 67: / Line 39: @@
 |[[Candida kefyr]]
 |0.25
+|
+|
@@ Line 78: / Line 44: @@
 |[[Candida krusei]]
 |0.5
+|
+|
@@ Line 89: / Line 49: @@
 |[[Candida lusitaniae]]
 |0.12
+|
+|
@@ Line 101: / Line 55: @@
 |0.25
 |≤0.06
 |≥0.12
 |-
 |[[Candida tropicalis]]
 |0.12
 |≤0.06
 |≥0.12
 |-
 |[[Cryptococcus neoformans]]
+|
-| colspan="8" rowspan="2" |
+| colspan="4" rowspan="2" |
 |-
 |[[Cryptococcus gattii]]
+|
 |}

Aidan at 13:24, 30 March 2022

2022-03-30T13:24:58Z

@@ Line 127: / Line 127: @@
+|
 |}
 [[Category:Triazoles]]

Aidan: /* Clinical Breakpoints */

2021-01-20T01:55:26Z

Clinical Breakpoints

@@ Line 78: / Line 78: @@
 |[[Candida krusei]]
 |0.5
 |-
 |[[Candida lusitaniae]]

Aidan at 01:12, 20 January 2021

2021-01-20T01:12:28Z

@@ Line 5: / Line 5: @@
 *For treatment, target trough >1 mg/L
 {| class="wikitable"
-!Species
+! rowspan="2" |Species
-!ECV (mcg/mL)
+! rowspan="2" |ECV (μg/mL)
 |-
 |0.06
 |-
 |2
 |-
 |0.25
 |-
 |0.12
 |-
-|0.5
+|0.25
 |-
 |0.12
 |-
-|0.5
 |-
 |}
 [[Category:Triazoles]]

Aidan: /* Therapeutic Drug Monitoring */

2021-01-19T16:00:54Z

Therapeutic Drug Monitoring

← Older revision		Revision as of 16:00, 19 January 2021
Line 1:		Line 1:
	== Therapeutic Drug Monitoring ==		==Therapeutic Drug Monitoring==
⚫	* Measure trough 7 days after starting or adjusting dose, or adjusting interacting medications, or concerns of poor adherence or absorption
⚫	* For prophylaxis, target trough >0.7 mg/L, or random level 0.35 mg/L 48 h after starting therapy
⚫	* For treatment, target trough >1 mg/L

		⚫	*Measure trough 7 days after starting or adjusting dose, or adjusting interacting medications, or concerns of poor adherence or absorption
		⚫	*For prophylaxis, target trough >0.7 mg/L, or random level 0.35 mg/L 48 h after starting therapy
		⚫	*For treatment, target trough >1 mg/L

			=== Epidemiologic Cutoff Values ===
			{\| class="wikitable"
			!Species
			!ECV (mcg/mL)
			\|-
			\|C. albicans
			\|0.06
			\|-
			\|C. glabrata
			\|2
			\|-
			\|C. parapsilosis
			\|0.25
			\|-
			\|C. tropicalis
			\|0.12
			\|-
			\|C. krusei
			\|0.5
			\|-
			\|C. lusitaniae
			\|0.12
			\|-
			\|C. guilliermondii
			\|0.5
			\|-
			\|C. kefyr
			\|0.25
			\|}
	[[Category:Triazoles]]		[[Category:Triazoles]]

Aidan at 11:01, 26 August 2020

2020-08-26T11:01:49Z

← Older revision		Revision as of 11:01, 26 August 2020
Line 4:		Line 4:
	* For treatment, target trough >1 mg/L		* For treatment, target trough >1 mg/L

	[[Category:~~Antifungals~~]]		[[Category:Triazoles]]

Aidan: Created page with "== Therapeutic Drug Monitoring == * Measure trough 7 days after starting or adjusting dose, or adjusting interacting medications, or concerns of poor adherence or absorption *..."

2019-11-21T01:43:57Z

Created page with "== Therapeutic Drug Monitoring == * Measure trough 7 days after starting or adjusting dose, or adjusting interacting medications, or concerns of poor adherence or absorption *..."

New page

== Therapeutic Drug Monitoring ==
* Measure trough 7 days after starting or adjusting dose, or adjusting interacting medications, or concerns of poor adherence or absorption
* For prophylaxis, target trough >0.7 mg/L, or random level 0.35 mg/L 48 h after starting therapy
* For treatment, target trough >1 mg/L

[[Category:Antifungals]]