Opioid withdrawal - Revision history

Aidan: Text replacement - "Clinical Presentation" to "Clinical Manifestations"

2020-07-20T19:30:21Z

Text replacement - "Clinical Presentation" to "Clinical Manifestations"

← Older revision		Revision as of 19:30, 20 July 2020
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	==Clinical ~~Presentation~~==		==Clinical Manifestations==

	*Onset of symptoms depends on time from last dose and the half-life of the opioid		*Onset of symptoms depends on time from last dose and the half-life of the opioid

Aidan at 16:19, 9 July 2020

2020-07-09T16:19:54Z

← Older revision		Revision as of 16:19, 9 July 2020
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	==Clinical Presentation==		==Clinical Presentation==

	* Onset of symptoms depends on time from last dose and the half-life of the opioid		*Onset of symptoms depends on time from last dose and the half-life of the opioid
	** Short-acting opioids ([[heroin]], [[morphine]], [[hydrocodone]], immediate-release [[oxycodone]]): 12 to 16 hours from last dose
	** ~~Intermediate~~-acting opioids ([[~~slow-release oral~~ morphine]], ~~controlled-release~~ [[~~hydromorphone~~]], ~~sustained~~-release [[oxycodone]]): 17 to 24 hours from last dose		**Short-acting opioids ([[heroin]], [[morphine]], [[hydrocodone]], immediate-release [[oxycodone]]): 12 to 16 hours from last dose
	** ~~Long~~-acting opioids ([[~~methadone~~]]): 24 to 48 hours from last dose		**Intermediate-acting opioids ([[slow-release oral morphine]], controlled-release [[hydromorphone]], sustained-release [[oxycodone]]): 17 to 24 hours from last dose
			**Long-acting opioids ([[methadone]]): 24 to 48 hours from last dose
	* Symptoms progress over time, and vary with the patient, their health status, their frequency, duration, and amount of use, and any concurrent substance use		*Symptoms progress over time, and vary with the patient, their health status, their frequency, duration, and amount of use, and any concurrent substance use
	** Within the first 6 to 12 hours: cravings, anxiety, anorexia, irritability, tachypnea, hypertension, sweating, yawning, lacrimation, rhinorrhea, piloerection, tremor, and dilated pupils
	** Within 24 to 48 hours: ~~nausea~~, ~~vomiting~~, ~~insomnia~~, ~~tachycardia~~, ~~abdominal~~ ~~cramps~~, ~~and~~ ~~involuntary~~ ~~muscle~~ ~~spasms~~ and ~~limb~~ ~~movements~~		**Within the first 6 to 12 hours: cravings, anxiety, anorexia, irritability, tachypnea, hypertension, sweating, yawning, lacrimation, rhinorrhea, piloerection, tremor, and dilated pupils
			**Within 24 to 48 hours: nausea, vomiting, insomnia, tachycardia, abdominal cramps, and involuntary muscle spasms and limb movements
	* Persistent symptoms usually resolve over 5 to 7 days		*Persistent symptoms usually resolve over 5 to 7 days
	* However, cravings, depression, irritability, and dysphoria may persist for weeks to months		*However, cravings, depression, irritability, and dysphoria may persist for weeks to months

			=== Precipitated withdrawal ===

			* Occurs when [[buprenorphine]] or another partial opiate agonist is started while there is a full agonist still active

	==Diagnosis==		==Diagnosis==

⚫	* [[~~Clinical~~ opioid withdrawal scale]] (~~COWS~~)
	* [[~~Subjective~~ opioid withdrawal scale]] (~~SOWS~~)		*[[Clinical opioid withdrawal scale]] (COWS)
		⚫	*[[Subjective opioid withdrawal scale]] (SOWS)

	[[Category:Addiction medicine]]		[[Category:Addiction medicine]]

Aidan: Created page with "==Clinical Presentation== * Onset of symptoms depends on time from last dose and the half-life of the opioid ** Short-acting opioids (heroin, morphine, hydrocodone..."

2020-07-09T16:15:32Z

Created page with "==Clinical Presentation== * Onset of symptoms depends on time from last dose and the half-life of the opioid ** Short-acting opioids (heroin, morphine, hydrocodone..."

New page

==Clinical Presentation==
* Onset of symptoms depends on time from last dose and the half-life of the opioid
** Short-acting opioids ([[heroin]], [[morphine]], [[hydrocodone]], immediate-release [[oxycodone]]): 12 to 16 hours from last dose
** Intermediate-acting opioids ([[slow-release oral morphine]], controlled-release [[hydromorphone]], sustained-release [[oxycodone]]): 17 to 24 hours from last dose
** Long-acting opioids ([[methadone]]): 24 to 48 hours from last dose
* Symptoms progress over time, and vary with the patient, their health status, their frequency, duration, and amount of use, and any concurrent substance use
** Within the first 6 to 12 hours: cravings, anxiety, anorexia, irritability, tachypnea, hypertension, sweating, yawning, lacrimation, rhinorrhea, piloerection, tremor, and dilated pupils
** Within 24 to 48 hours: nausea, vomiting, insomnia, tachycardia, abdominal cramps, and involuntary muscle spasms and limb movements
* Persistent symptoms usually resolve over 5 to 7 days
* However, cravings, depression, irritability, and dysphoria may persist for weeks to months

==Diagnosis==
* [[Clinical opioid withdrawal scale]] (COWS)
* [[Subjective opioid withdrawal scale]] (SOWS)

[[Category:Addiction medicine]]