Aidan: Created page with "== Background == === Microbiology === * Group B Streptococcus * Escherichia coli * Other gram-negative bacteria === Pathophysiology === * Thought to be general..."

2022-02-02T19:02:26Z

Created page with "== Background == === Microbiology === * Group B Streptococcus * Escherichia coli * Other gram-negative bacteria === Pathophysiology === * Thought to be general..."

New page

== Background ==

=== Microbiology ===

* [[Group B Streptococcus]]
* [[Escherichia coli]]
* Other [[gram-negative bacteria]]

=== Pathophysiology ===

* Thought to be generally acquired vertically during birth from the genitourinary tract

== Clinical Manifestations ==

* May be just a fever
* Fussiness, lethargy, behavioural changes, decreased in frequency and volume of wet diapers, decreased feeding
* Tachypnea, tachycardia, fever, signs of dehydration, neurologic signs, increased work of breathing, jaundice
* WBC and CRP may be normal early in the course of illness despite severe bacterial infection

== Management ==

* An axillary temperature higher than 37.5ºC (rectal greater than 38ºC) in an infant younger than 3 months older should be investigated
* The [https://www.mdcalc.com/step-step-approach-febrile-infants PECARN Step by Step approach] can be used to identify patients at low risk, based on general appearance, age ≤21 days, leukocyturia, procalcitonin ≥0.5 ng/mL, and CRP > 20 mg/L or ANC > 10

[[Category:Pediatrics]]
[[Category:Fever syndromes]]

Neonatal sepsis - Revision history

Aidan: Created page with "== Background == === Microbiology === * Group B Streptococcus * Escherichia coli * Other gram-negative bacteria === Pathophysiology === * Thought to be general..."